Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 4/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL593934 | 0.80 | PI4KA (0.54) | TSHRPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4201094 | 0.77 | PNP (0.42) | — | |
| SCHEMBL8566 | 0.75 | ADORA2A (1.00) | ADORA1ADORA2ATSHRPI4KAPI4K2B | |
| SCHEMBL29529372 | 0.75 | ADORA2A (1.00) | ADORA1ADORA2ATSHRPI4KAPI4K2B | |
| SCHEMBL15602792 | 0.73 | PDPK1 (0.40) | ADORA1ADORA2ACDK1CCNB1CCNA2 | |
| 2,6-Diaminopurine SCHEMBL443468 | 0.72 | PDPK1 (0.55) | ADORA1ADORA2ACDK1CCNB1CCNA2 | |
| SCHEMBL9443837 | 0.72 | NADK (0.63) | HSD17B10CDK1CCNB1CCNA2CDK2 | |
| Guanine SCHEMBL4198112 | 0.70 | PNP (0.58) | ALDH1A1HSD17B10 | |
| SCHEMBL11315629 | 0.69 | HIF1A (0.48) | ADORA1ADORA2ATSHRPI4KAPI4K2B | |
| SCHEMBL4199979 | 0.69 | PNP (0.32) | ALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608402-B2 | DNA methylation specific signal amplification | LI WEIWEI | 2009-10-27 | — | — | US | disclosed |
| US-20090181373-A1 | DNA methylation specific signal amplification | LI WEIWEI | 2009-07-16 | — | — | US | disclosed |