SCHEMBL4201094

SCHEMBL4201094

Nc1nc2nc(Br)[nH]c2c(=O)[nH]1.OC[C@H]1OC[C@H](O)[C@@H]1O

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PNP P00491 5/20 0.42
TXN P10599 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Guanine SCHEMBL4198112 0.81 PNP (0.58) PNPMEN1KMT2A
SCHEMBL4194716 0.79 MAPT (0.55) PNPMEN1KMT2A
SCHEMBL4201092 0.77 ADORA1 (0.57)
SCHEMBL9116 0.75 PNP (0.73) PNPMEN1KMT2A
SCHEMBL10607653 0.75 PNP (0.39) PNPMEN1KMT2A
SCHEMBL8071957 0.73 PNP (0.49) PNPTXNMEN1KMT2A
SCHEMBL6551875 0.73 PNP (0.49) PNPTXNMEN1KMT2A
SCHEMBL6551935 0.73 PNP (0.49) PNPTXNMEN1KMT2A
SCHEMBL8785781 0.73 PNP (0.49) PNPTXNMEN1KMT2A
SCHEMBL7032324 0.73 PNP (0.49) PNPTXNMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7608402-B2 DNA methylation specific signal amplification LI WEIWEI 2009-10-27 US disclosed
US-20090181373-A1 DNA methylation specific signal amplification LI WEIWEI 2009-07-16 US disclosed