Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.71 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 9/20 | 0.50 |
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARD | Q03181 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204493 | 0.94 | FFAR4 (0.59) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL15692650 | 0.93 | FFAR4 (0.73) | FFAR4FFAR1FAAHGPR84PPARG | |
| SCHEMBL1134727 | 0.93 | FFAR4 (0.73) | FFAR4FFAR1FAAHGPR84PPARG | |
| SCHEMBL4201646 | 0.91 | MAPK1 (0.58) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL29160513 | 0.90 | FFAR4 (0.69) | FFAR4FFAR1FAAHGPR84TSHR | |
| SCHEMBL29175263 | 0.90 | FFAR4 (0.68) | FFAR4FFAR1FAAHGPR84TSHR | |
| SCHEMBL27949697 | 0.89 | FFAR4 (0.50) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL3403797 | 0.88 | FFAR4 (0.66) | FFAR4FFAR1FAAHGPR84PPARG | |
| SCHEMBL10695256 | 0.88 | FFAR4 (0.66) | FFAR4FFAR1FAAHGPR84TSHR | |
| SCHEMBL5972507 | 0.86 | FFAR4 (0.63) | FFAR4FFAR1TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7491836-B2 | Non-ionic surfactants for poorly soluble molecules | ASTRAZENECA AB (SE) | 2009-02-17 | — | — | US | disclosed |
| US-20060287542-A1 | Non-ionic surfactants for solubilizing poorly solubule molecules | ASTRAZENECA AB (SE) | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287542-A1 | Non-ionic surfactants for solubilizing poorly solubule molecules | LIPA, ELOVL1, FASN | FFAR4 137/4885FFAR1 29/4885FAAH 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.