Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115139 | 0.81 | NPSR1 (0.56) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL16599595 | 0.81 | ALDH1A1 (0.55) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL4201822 | 0.77 | NPSR1 (0.52) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL11848125 | 0.77 | ALDH1A1 (0.42) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL2728438 | 0.75 | ALDH1A1 (0.47) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL560266 | 0.74 | NPSR1 (0.48) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL20360661 | 0.73 | ALDH1A1 (0.55) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL3730131 | 0.72 | NPSR1 (0.50) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL938835 | 0.72 | NPC1 (0.44) | NPSR1ALDH1A1KMT2ANPC1HTT | |
| SCHEMBL1058455 | 0.70 | ALDH1A1 (0.40) | NPSR1ALDH1A1KMT2ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044309-A2 | DEVICE AND METHOD FOR INHIBITING AGE COMPLEX FORMATION | VASIX CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |