Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4202161 | 1.00 | GPR88 (0.38) | GPR88POLBMEN1KMT2AFFAR1 | |
| SCHEMBL4205633 | 0.93 | POLB (0.40) | POLBMEN1KMT2AFFAR1 | |
| SCHEMBL4205630 | 0.93 | POLB (0.40) | POLBMEN1KMT2AFFAR1 | |
| SCHEMBL4192242 | 0.91 | FFAR1 (0.42) | MEN1KMT2AFFAR1LMNAALOX5 | |
| SCHEMBL4192246 | 0.91 | FFAR1 (0.42) | MEN1KMT2AFFAR1LMNAALOX5 | |
| SCHEMBL4192216 | 0.87 | ALDH1A1 (0.40) | GPR88POLBMEN1KMT2ALMNA | |
| SCHEMBL4192209 | 0.87 | ALDH1A1 (0.40) | GPR88POLBMEN1KMT2ALMNA | |
| SCHEMBL5188655 | 0.87 | ALDH1A1 (0.40) | GPR88POLBMEN1KMT2ALMNA | |
| SCHEMBL2847080 | 0.85 | POLB (0.43) | POLBMEN1KMT2A | |
| SCHEMBL20212169 | 0.85 | POLB (0.43) | POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247743-A1 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | PFIZER INC | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247743-A1 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | SCN2A, SCN1A, ORAI2 | GPR88 1236/4885POLB 2428/4885MEN1 2322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.