SCHEMBL4202185

SCHEMBL4202185

CCC(C)Oc1ccc(-n2nnnc2C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.47
PRMT1 Q99873 3/20 0.43
NPSR1 Q6W5P4 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NOTUM Q6P988 1/20 0.39
MAPT P10636 3/20 0.38
RAB9A P51151 2/20 0.38
TSHR P16473 1/20 0.38
ALDH1A1 P00352 4/20 0.38
TP53 P04637 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
NLRP1 Q9C000 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 1/20 0.37
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4203124 0.85 ALDH1A1 (0.45) LMNANPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL4209166 0.84 PRMT1 (0.53) LMNAPRMT1NPSR1SMN1; SMN2MEN1
SCHEMBL4204758 0.84 PRMT1 (0.51) LMNAPRMT1NPSR1SMN1; SMN2MEN1
SCHEMBL4207119 0.84 MAPT (0.43) LMNAPRMT1NPSR1SMN1; SMN2MEN1
SCHEMBL4203146 0.83 PRMT1 (0.50) LMNAPRMT1NPSR1SMN1; SMN2MEN1
SCHEMBL4199018 0.81 PRMT1 (0.40) PRMT1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL4208686 0.79 PRMT1 (0.39) PRMT1NPSR1SMN1; SMN2MEN1KMT2A
SCHEMBL4210492 0.78 MAPT (0.57) LMNANPSR1SMN1; SMN2KMT2ANOTUM
SCHEMBL4202372 0.78 LMNA (0.48) LMNAPRMT1NPSR1SMN1; SMN2KMT2A
SCHEMBL24240345 0.77 LMNA (0.62) LMNANPSR1MEN1KMT2ANOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7579480-B2 Alkoxy-(tetrazol-1-yl)benzaldehyde compound and process for producing the same TOYO KASEI KOGYO COMPANY LIMITED (JP) 2009-08-25 US disclosed
US-20070060630-A1 Alkoxy-(tetrazol-1-yl)benzaldehyde compound and process for producing the same TOYO KASEI KOGYO COMPANY LIMITED (JP) 2007-03-15 US disclosed
EP-1650198-A1 ALKOXYTETRAZOL-1-YLBENZALDEHYDE COMPOUND AND PROCESS FOR PRODUCING THE SAME Toyo Kasei Kogyo Company Limited (JP) 2006-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070060630-A1 Alkoxy-(tetrazol-1-yl)benzaldehyde compound and process for producing the same ALDH7A1, NAT1, ARSA LMNA 2434/4885PRMT1 1901/4885NPSR1 2735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.