SCHEMBL4202500

SCHEMBL4202500

CCO[Si](NC1CCCCC1)(OCC)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.34
SHBG P04278 1/20 0.33
THRB P10828 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALDH1A1 P00352 2/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 2/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
EPHX2 P34913 1/20 0.31
KDM4E B2RXH2 1/20 0.31
HSD17B10 Q99714 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4201538 0.98 EPHX1 (0.32) EPHX1SHBGTHRBATML3MBTL1
SCHEMBL4207183 0.86 CYP1A2 (0.34) EPHX1SHBGALDH1A1KDM4E
SCHEMBL4202486 0.86 EPHX1 (0.36) EPHX1SHBGTHRBATML3MBTL1
SCHEMBL4213046 0.84 CYP1A2 (0.35) EPHX1
SCHEMBL4211819 0.84 EPHX1 (0.33) EPHX1SHBG
SCHEMBL4209691 0.79 ALDH1A1 (0.33) EPHX1ATMALDH1A1NPSR1MMP2
SCHEMBL4211427 0.77 SMN1; SMN2 (0.34) EPHX1ALDH1A1KDM4E
SCHEMBL4213061 0.76
SCHEMBL28995357 0.76 THRB (0.36) EPHX1SHBGTHRBATML3MBTL1
SCHEMBL721676 0.76 THRB (0.36) EPHX1SHBGTHRBATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253873-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME TOHO CATALYST CO., LTD (JP) 2009-10-08 US disclosed
EP-1829898-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME Toho Catalyst Co., Ltd. (JP) 2007-09-05 EP disclosed