SCHEMBL4202913

SCHEMBL4202913

COC(=O)C(CC(C)C)NC(=O)c1ccc2occc2c1.COC(=O)[C@@H](CC(C)C)NC(=O)c1ccc2occc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 20/20 1.00
TAS1R1 Q7RTX1 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10226453 1.00 TAS1R3 (1.00) TAS1R3TAS1R1
SCHEMBL702029 1.00 TAS1R3 (1.00) TAS1R3TAS1R1
SCHEMBL20662748 0.88 TAS1R3 (0.78) TAS1R3TAS1R1
SCHEMBL12597087 0.82 TAS1R3 (0.70) TAS1R3TAS1R1
SCHEMBL4211753 0.81 TAS1R3 (0.71) TAS1R3TAS1R1
SCHEMBL11918871 0.81 TAS1R3 (0.71) TAS1R3TAS1R1
SCHEMBL4211750 0.81 TAS1R3 (0.71) TAS1R3TAS1R1
SCHEMBL4197753 0.79 TAS1R3 (1.00) TAS1R3TAS1R1
SCHEMBL4197755 0.79 TAS1R3 (1.00) TAS1R3TAS1R1
SCHEMBL27601966 0.79 TAS1R3 (0.65) TAS1R3TAS1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1659881-B1 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF SENOMYX INC (US) 2019-04-03 EP disclosed
EP-3431464-A2 NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF Senomyx Inc. (US) 2019-01-23 EP disclosed
US-7476399-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX INC. (US) 2009-01-13 US disclosed