Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.65 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.65 |
| ▸ | HTR1B | P28222 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.47 |
| ▸ | WNT3A | P56704 | 6/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.42 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821662 | 0.87 | TAS1R3 (0.60) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL2819877 | 0.84 | TAS1R3 (0.55) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL20662748 | 0.81 | TAS1R3 (0.78) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL10226453 | 0.79 | TAS1R3 (1.00) | TAS1R3TAS1R1 | |
| SCHEMBL702029 | 0.79 | TAS1R3 (1.00) | TAS1R3TAS1R1 | |
| SCHEMBL4202913 | 0.79 | TAS1R3 (1.00) | TAS1R3TAS1R1 | |
| SCHEMBL5210394 | 0.77 | CA2 (0.49) | CA1CA2 | |
| SCHEMBL13516717 | 0.77 | CTNNB1 (0.61) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL30791009 | 0.77 | CTNNB1 (0.61) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL5118660 | 0.77 | CA2 (0.49) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100540538-C | High Conductivity Calcium-Activated K Channel Opener | TANABE SEIYAKU CO (JP) | 2009-09-16 | — | — | CN | disclosed |
| CN-101519386-A | High Conductivity Calcium-Activated K Channel Opener | TANABE SEIYAKU CO (JP) | 2009-09-02 | — | — | CN | disclosed |
| CN-1503786-A | High Conductivity Calcium-Activated K Channel Opener | ������ҩ��ʽ���� | 2004-06-09 | — | — | CN | disclosed |