Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195104 | 0.93 | CYP4F2 (0.33) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL4206187 | 0.93 | CYP4F2 (0.33) | CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL4334068 | 0.79 | CYP2C19 (0.39) | CYP4F2CYP4A11MMP2 | |
| SCHEMBL4339942 | 0.70 | SLC6A2 (0.36) | CYP4F2CYP4A11 | |
| SCHEMBL2298802 | 0.70 | SLC6A2 (0.36) | CYP4F2CYP4A11 | |
| SCHEMBL29156971 | 0.67 | CYP4F2 (0.38) | CYP4F2CYP4A11 | |
| SCHEMBL5634801 | 0.66 | CYP2D6 (0.38) | CYP4F2CYP4A11 | |
| SCHEMBL211627 | 0.65 | ALDH1A1 (0.58) | ALDH1A1MMP13 | |
| SCHEMBL3557213 | 0.63 | — | — | |
| SCHEMBL29143899 | 0.63 | RAB9A (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032559-A1 | 2-HETEROCYCLOAMINO-4-IMIDAZOLYLPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION | AstraZeneca AB (SE) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007138268-A1 | 2-HETEROCYCLOAMINO-4-IMIDAZOLYLPYRIMIDINES AS AGENTS FOR THE INHIBITION OF CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2007-12-06 | — | — | WO | disclosed |