Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
| ▸ | CCR3 | P51677 | 3/20 | 0.53 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6160526 | 1.00 | GBA1 (0.59) | GBA1CCR3PRMT3CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL30304790 | 0.98 | GBA1 (0.57) | GBA1CCR3PRMT3CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL29210829 | 0.98 | GBA1 (0.57) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL674276 | 0.89 | GBA1 (0.71) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL2027845 | 0.89 | GBA1 (0.71) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL13936369 | 0.88 | GBA1 (0.50) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL3898572 | 0.88 | GBA1 (0.50) | GBA1CCR3PRMT3CARM1PRMT6 | |
| Ammonia Solution, Strong SCHEMBL1432566 | 0.86 | GBA1 (0.68) | GBA1CCR3PRMT3CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL4797146 | 0.84 | GBA1 (0.65) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL5525774 | 0.83 | GBA1 (0.59) | GBA1CCR3PRMT3CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087066-A | Haloaryl Substituted Aminopurines, Compositions Thereof, And Methods Of Treatment Therewith | PHARMACOPEIA DRUG DISCOVERY | 2013-05-08 | — | — | CN | disclosed |
| EP-2029578-A1 | 2-CARBOCYCLOAMINO-4-IMIDAZ0LYLPYRIMIDINES AS AGENTS FOR THE INHBITION OF CELL PROLIFERATION | AstraZeneca AB (SE) | 2009-03-04 | — | — | EP | disclosed |
| CN-101142215-A | Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith | SIGNAL PHARM LLC (US) | 2008-03-12 | — | — | CN | disclosed |
| WO-2007138277-A1 | 2-CARBOCYCLOAMINO-4-IMIDAZ0LYLPYRIMIDINES AS AGENTS FOR THE INHBITION OF CELL PROLIFERATION | ASTRAZENECA AB (SE) | 2007-12-06 | — | — | WO | disclosed |