Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.59 |
| ▸ | CCR3 | P51677 | 3/20 | 0.53 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.53 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.53 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.53 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203449 | 1.00 | GBA1 (0.59) | GBA1CCR3PRMT3CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL30304790 | 0.98 | GBA1 (0.57) | GBA1CCR3PRMT3CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL29210829 | 0.98 | GBA1 (0.57) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL674276 | 0.89 | GBA1 (0.71) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL2027845 | 0.89 | GBA1 (0.71) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL13936369 | 0.88 | GBA1 (0.50) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL3898572 | 0.88 | GBA1 (0.50) | GBA1CCR3PRMT3CARM1PRMT6 | |
| Ammonia Solution, Strong SCHEMBL1432566 | 0.86 | GBA1 (0.68) | GBA1CCR3PRMT3CARM1PRMT6 | |
| Hydrochloric Acid SCHEMBL4797146 | 0.84 | GBA1 (0.65) | GBA1CCR3PRMT3CARM1PRMT6 | |
| SCHEMBL5525774 | 0.83 | GBA1 (0.59) | GBA1CCR3PRMT3CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250122542-A1 | PROCESS TO PRODUCE (1R,4R)-4-SUBSTITUTED CYCLOHEXANE-1-AMINES | RICHTER GEDEON NYRT (HU) | 2025-04-17 | — | — | US | disclosed |
| EP-4402276-A1 | PROCESS TO PRODUCE (1 R, 4 R)-4-SUBSTITUTED CYCLOHEXANE-1-AMINES | Richter Gedeon Nyrt. (HU) | 2024-07-24 | — | — | EP | disclosed |
| CN-118043471-A | Process for the production of (1 r,4 r) -4-substituted cyclohexane-1-amines | 吉瑞工厂 | 2024-05-14 | — | — | CN | disclosed |
| US-20240018119-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | TRINEURO (KR) | 2024-01-18 | — | — | US | disclosed |
| US-20240018119-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | TRINEURO (KR) | 2024-01-18 | — | — | US | disclosed |
| WO-2023042081-A1 | PROCESS TO PRODUCE (1r,4r)-4-SUBSTITUTED CYCLOHEXANE-1-AMINES | RICHTER GEDEON NYRT. (HU) | 2023-03-23 | — | — | WO | disclosed |
| CN-104859223-A | Adhesive-free FCCL (flexible copper-clad laminate) with two medium layers | CHENGDU DO IT NEW MATERIAL CO LTD | 2015-08-26 | — | — | CN | disclosed |
| CN-104842625-A | Preparation method of two-layer dielectric adhesive-free flexible copper clad laminate | CHENGDU DO IT NEW MATERIAL CO LTD | 2015-08-19 | — | — | CN | disclosed |
| CN-103087066-A | Haloaryl Substituted Aminopurines, Compositions Thereof, And Methods Of Treatment Therewith | PHARMACOPEIA DRUG DISCOVERY | 2013-05-08 | — | — | CN | disclosed |
| US-20110021448-A1 | Inhibitors for the Soluble Epoxide Hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-01-27 | — | — | US | disclosed |
| US-6291499-B1 | TREATING MIGRAINE, DEPRESSION, ANXIETY, SCHIZOPHRENIA, PARKINSON'S DISEASE, OR STROKE | MERCK & CO., INC. | 2001-09-18 | — | — | US | disclosed |
| WO-2001032634-A1 | 2-CYCLOHEXYL BENZIMIDAZOLE NMDA/NR2B ANTAGONISTS | MERCK & CO., INC. (US) | 2001-05-10 | — | — | WO | disclosed |
| US-6204260-B1 | 2-(AZETIDIN-2-ON-1-YL)ACETIC ACID DERIVATIVES | ELI LILLY AND COMPANY | 2001-03-20 | — | — | US | disclosed |
| EP-0743936-B1 | CYCLOHEXANE DERIVATIVES AS VOLTAGE-GATED POTASSIUM CHANNEL BLOCKERS | WYETH JOHN & BROTHER LTD (GB) | 2000-06-14 | — | — | EP | disclosed |
| US-5948881-A | LOW VISCOSITY, HIGH DRYING SPEED, EPOXY RESINS/POLYEPOXIDES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1999-09-07 | — | — | US | disclosed |
| US-5852023-A | Cyclohexylamino and cycloalkoxy nitrogen heterocycles, processes for their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| EP-0817774-A1 | CYCLOHEXYLAMINO AND CYCLOHEXYLALKOXY NITROGEN HETEROCYCLES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030345-A1 | CYCLOHEXYLAMINO AND CYCLOHEXYLALKOXY NITROGEN HETEROCYCLES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-10-03 | — | — | WO | disclosed |
| US-4041053-A | DYES OR INTERMEDIATES THEREFOR | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |
| US-3980677-A | Anthraquinone dyestuffs containing sulphonic acid groups | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021448-A1 | Inhibitors for the Soluble Epoxide Hydrolase | EPHX1, EPHX2, NCEH1 | GBA1 1191/4885CCR3 2998/4885PRMT3 3162/4885 |
| US-20240018119-A1 | CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | MAOA, DRD2, MAOB | GBA1 1662/4885CCR3 4856/4885PRMT3 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.