SCHEMBL420464

SCHEMBL420464

O=C1N[C@H]2[C@H](CS[C@H]2CCCC(=O)C(=O)O)N1

nearest known ligand 0.72

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.72
▸ MEN1 O00255 1/20 0.72
▸ ABL1 P00519 1/20 0.72
▸ LMNA P02545 1/20 0.72
▸ PKM P14618 1/20 0.72
▸ IDE P14735 1/20 0.72
▸ MAPK1 P28482 1/20 0.72
▸ KMT2A Q03164 1/20 0.72
▸ RIN1 Q13671 1/20 0.72
▸ L3MBTL1 Q9Y468 1/20 0.72
▸ HLCS P50747 6/20 0.63
▸ CA12 O43570 7/20 0.52
▸ CA1 P00915 7/20 0.52
▸ CA2 P00918 7/20 0.52
▸ CA9 Q16790 7/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13958687 0.88 TDP1 (0.91) TDP1MEN1ABL1LMNAPKM
SCHEMBL4314463 0.88 TDP1 (0.91) TDP1MEN1ABL1LMNAPKM
SCHEMBL16900247 0.88 TDP1 (0.91) TDP1MEN1ABL1LMNAPKM
SCHEMBL16379530 0.88 TDP1 (0.91) TDP1MEN1ABL1LMNAPKM
SCHEMBL9557437 0.86 TDP1 (0.69) TDP1MEN1ABL1LMNAPKM
SCHEMBL3262330 0.86 TDP1 (0.69) TDP1MEN1ABL1LMNAPKM
SCHEMBL8081758 0.85 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL8164531 0.84 TDP1 (0.75) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23055065 0.84 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL20547409 0.84 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 762 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4416303-A1 A MICROSPHERE COMPRISING A FIRST MATERIAL AND A SECOND MATERIAL Blink AG (DE) 2024-08-21 — — EP claimed
CN-118510909-A Microsphere comprising a first material and a second material 布林克公司 2024-08-16 — — CN claimed
US-20240084354-A1 MEANS AND METHODS FOR REGULATING INTRACELLULAR TRAFFICKING OF SECRETORY OR CELL MEMBRANE-ANCHORED PROTEINS OF INTEREST HONING BIOSCIENCES (FR) 2024-03-14 — — US claimed
EP-4244240-A1 MEANS AND METHODS FOR REGULATING INTRACELLULAR TRAFFICKING OF SECRETORY OR CELL MEMBRANE-ANCHORED PROTEINS OF INTEREST Honing Biosciences (FR) 2023-09-20 — — EP claimed
WO-2023154852-A1 ANTIBODY BARCODED BEADS AND USES THEREOF CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2023-08-17 — — WO claimed
WO-2023079140-A1 A MICROSPHERE COMPRISING A FIRST MATERIAL AND A SECOND MATERIAL BLINK AG (DE) 2023-05-11 — — WO claimed
EP-4177352-A1 A MICROSPHERE COMPRISING A FIRST MATERIAL AND A SECOND MATERIAL Blink AG (DE) 2023-05-10 — — EP claimed
US-20230126528-A1 A LIBRARY OF PREFABRICATED MICROPARTICLES AND PRECURSORS THEREOF BLINK AG (DE) 2023-04-27 — — US claimed
CN-110291095-B Adenosine analogues and their use in regulating circadian clock 北京生命科学研究所 2023-04-18 — — CN claimed
EP-4078180-A1 A LIBRARY OF PREFABRICATED MICROPARTICLES AND PRECURSORS THEREOF Blink AG (DE) 2022-10-26 — — EP claimed
US-20010023288-A1 Trifunctional reagent for conjugation to a biomolecule GLYCOREX TRANSPLANTATION AB (SE) 2001-09-20 — — US claimed
EP-1095274-A1 TRIFUNCTIONAL REAGENT FOR CONJUGATION TO A BIOMOLECULE Department of Radiation Oncology, University of Washington (US) 2001-05-02 — — EP claimed
WO-2000002051-A1 TRIFUNCTIONAL REAGENT FOR CONJUGATION TO A BIOMOLECULE DEPT. OF RADIATION ONCOLOGY, UNIVERSITY OF WASHINGTON (US) 2000-01-13 — — WO claimed
WO-2000002050-A1 TRIFUNCTIONAL REAGENT FOR CONJUGATION TO A BIOMOLECULE DEPARTMENT OF RADIATION ONCOLOGY, UNIVERSITY OF WASHINGTON (US) 2000-01-13 — — WO claimed
EP-0717848-A1 BIOTIN-ANALOG CONJUGATED ANTIBODIES FOR POSITIVE CELL SELECTION AND RELEASE BAXTER INTERNATIONAL INC. (US) 1996-06-26 — — EP claimed
WO-1995007466-A2 BIOTIN-ANALOG CONJUGATED ANTIBODIES FOR POSITIVE CELL SELECTION AND RELEASE BAXTER INTERNATIONAL INC. (US) 1995-03-16 — — WO claimed
US-5108921-A Contacting living cell membrane with complex of biotin and derivatives and biologically functional molecules; modifying cell function PURDUE RESEARCH FOUNDATION (US) 1992-04-28 — — US claimed
EP-0088542-B1 SKIN TREATMENT COMPOSITION UNILEVER N.V. (NL) 1988-05-11 — — EP claimed
US-4529587-A Using biotin antagonist LEVER BROTHERS COMPANY (US) 1985-07-16 — — US claimed
EP-0088542-A2 Skin treatment composition UNILEVER N.V. (NL) 1983-09-14 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010023288-A1 Trifunctional reagent for conjugation to a biomolecule CD40, UACA, CD47 TDP1 3897/4885MEN1 2988/4885ABL1 483/4885
US-20240084354-A1 MEANS AND METHODS FOR REGULATING INTRACELLULAR TRAFFICKING OF SECRETORY OR CELL MEMBRANE-ANCHORED PROTEINS OF INTEREST PHAX, SCAMP2, YIPF5 TDP1 2678/4885MEN1 2782/4885ABL1 4402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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