Biotin

Biotin

SCHEMBL20547409

O=C(O)CCCC[C@@H]1SC[C@H]2NC(=O)N[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 1.00
MEN1 O00255 1/20 1.00
ABL1 P00519 1/20 1.00
LMNA P02545 1/20 1.00
PKM P14618 1/20 1.00
IDE P14735 1/20 1.00
MAPK1 P28482 1/20 1.00
KMT2A Q03164 1/20 1.00
RIN1 Q13671 1/20 1.00
L3MBTL1 Q9Y468 1/20 1.00
HLCS P50747 6/20 0.69
CA12 O43570 7/20 0.56
CA1 P00915 7/20 0.56
CA2 P00918 7/20 0.56
CA9 Q16790 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL826595 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL5376391 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL36572 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL9841217 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL410686 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL59420 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL23055065 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL21981206 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL22943835 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL3384633 1.00 TDP1 (1.00) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340591-A1 COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE CONTAINING NOVEL COMPOUND ANYGEN CO LTD (KR) 2025-11-06 US disclosed
CN-117616034-A Composition for preventing or treating inflammatory bowel disease containing novel compounds 安尼根有限公司 2024-02-27 CN disclosed
EP-4317171-A1 COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE CONTAINING NOVEL COMPOUND Anygen Co., Ltd. (KR) 2024-02-07 EP disclosed
US-20230212222-A1 COMPOSITION FOR ANTI-DIABETES AND ANTI-OBESITY COMPRISING NOVEL COMPOUND ANYGEN CO., LTD. (KR) 2023-07-06 US disclosed
US-20230159661-A1 T CELL REDIRECTING BISPECIFIC ANTIBODIES FOR THE TREATMENT OF EGFR POSITIVE CANCERS Ichnos Sciences SA (CH) 2023-05-25 US disclosed
WO-2023038464-A1 COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE CONTAINING NOVEL COMPOUND 애니젠 주식회사 2023-03-16 WO disclosed
EP-4119570-A1 COMPOSITION FOR ANTI-DIABETES AND ANTI-OBESITY COMPRISING NOVEL COMPOUND Anygen Co., Ltd. (KR) 2023-01-18 EP disclosed
EP-3615571-A1 T CELL REDIRECTING BISPECIFIC ANTIBODIES FOR THE TREATMENT OF EGFR POSITIVE CANCERS Ichnos Sciences SA (CH) 2020-03-04 EP disclosed
CN-110831968-A T cell redirecting bispecific antibodies for the treatment of EGFR-positive cancer 伊克诺斯科学公司 2020-02-21 CN disclosed
WO-2018197502-A1 T CELL REDIRECTING BISPECIFIC ANTIBODIES FOR THE TREATMENT OF EGFR POSITIVE CANCERS GLENMARK PHARMACEUTICALS S.A. (CH) 2018-11-01 WO disclosed
CN-1420173-A High-temp. resistant biotin synthetase gene, polypeptide coded therewith and preparing method thereof HUADA GENE RES & DEV CT HANGZH (CN) 2003-05-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340591-A1 COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY BOWEL DISEASE CONTAINING NOVEL COMPOUND GPR39, FABP2, GPR119 TDP1 4831/4885MEN1 4772/4885ABL1 4137/4885
US-20230212222-A1 COMPOSITION FOR ANTI-DIABETES AND ANTI-OBESITY COMPRISING NOVEL COMPOUND GPR119, GPR39, FABP4 TDP1 4730/4885MEN1 4708/4885ABL1 4740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.