Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29475392 | 0.95 | BRD4 (0.32) | BRD4GAAALDH1A1 | |
| SCHEMBL21904733 | 0.95 | BRD4 (0.32) | BRD4 | |
| SCHEMBL28958356 | 0.93 | BRD4 (0.31) | BRD4 | |
| SCHEMBL21318403 | 0.84 | SIRT2 (0.33) | BRD4GAAALDH1A1SIRT2KDM4E | |
| SCHEMBL241113 | 0.82 | FAAH (0.36) | BRD4SIRT2LMNA | |
| SCHEMBL29359375 | 0.82 | FAAH (0.36) | BRD4SIRT2LMNA | |
| SCHEMBL3127639 | 0.81 | ALDH1A1 (0.47) | GAAALDH1A1KDM4EHPSECYP1A2 | |
| Hydrochloric Acid SCHEMBL29673290 | 0.81 | FAAH (0.36) | BRD4 | |
| SCHEMBL19458902 | 0.81 | FAAH (0.36) | BRD4 | |
| Fluoride Ion SCHEMBL542371 | 0.81 | FAAH (0.36) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3980057-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | Institut Curie (FR) | 2022-04-13 | — | — | EP | disclosed |
| EP-1687318-A4 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS | UNIV MASSACHUSETTS (US) | 2009-01-07 | — | — | EP | disclosed |
| EP-1687318-A2 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS | University of Massachusetts (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005042562-A2 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS | THE UNIVERSITY OF MASSACHUSETTS (US) | 2005-05-12 | — | — | WO | disclosed |