Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205777 | 1.00 | GPR84 (0.58) | GPR84SLC22A6FFAR4ACE2FFAR1 | |
| SCHEMBL8075102 | 1.00 | GPR84 (0.58) | GPR84SLC22A6FFAR4ACE2FFAR1 | |
| SCHEMBL5165829 | 1.00 | GPR84 (0.58) | GPR84SLC22A6FFAR4ACE2FFAR1 | |
| SCHEMBL25184389 | 0.93 | GPR84 (0.70) | GPR84SLC22A6FFAR4ACE2FFAR1 | |
| SCHEMBL8322086 | 0.93 | GPR84 (0.70) | GPR84SLC22A6FFAR4ACE2FFAR1 | |
| SCHEMBL25204772 | 0.93 | GPR84 (0.70) | GPR84SLC22A6FFAR4ACE2FFAR1 | |
| SCHEMBL4195639 | 0.88 | GPR84 (0.52) | GPR84SLC22A6FFAR4FFAR1MAPT | |
| SCHEMBL4206035 | 0.88 | GPR84 (0.52) | GPR84SLC22A6FFAR4FFAR1MAPT | |
| SCHEMBL665787 | 0.88 | GPR84 (0.52) | GPR84SLC22A6FFAR4FFAR1MAPT | |
| SCHEMBL4747859 | 0.88 | GPR84 (0.52) | GPR84SLC22A6FFAR4FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247743-A1 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | PFIZER INC | 2009-10-01 | — | — | US | claimed |
| US-20090247743-A1 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | PFIZER INC | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247743-A1 | PREPARATION OF BETA-AMINO ACIDS HAVING AFFINITY FOR THE ALPHA-2-DELTA PROTEIN | SCN2A, SCN1A, ORAI2 | GPR84 2070/4885SLC22A6 1693/4885FFAR4 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.