SCHEMBL8075102

SCHEMBL8075102

CCCC[C@@H](C)C[C@H](O)CC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 5/20 0.58
SLC22A6 Q4U2R8 1/20 0.44
FFAR4 Q5NUL3 1/20 0.43
ACE2 Q9BYF1 1/20 0.43
FFAR1 O14842 1/20 0.43
MAPT P10636 2/20 0.39
CA2 P00918 1/20 0.39
MAPK1 P28482 1/20 0.39
GABRR1 P24046 2/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4205777 1.00 GPR84 (0.58) GPR84SLC22A6FFAR4ACE2FFAR1
SCHEMBL4205656 1.00 GPR84 (0.58) GPR84SLC22A6FFAR4ACE2FFAR1
SCHEMBL5165829 1.00 GPR84 (0.58) GPR84SLC22A6FFAR4ACE2FFAR1
SCHEMBL25184389 0.93 GPR84 (0.70) GPR84SLC22A6FFAR4ACE2FFAR1
SCHEMBL8322086 0.93 GPR84 (0.70) GPR84SLC22A6FFAR4ACE2FFAR1
SCHEMBL25204772 0.93 GPR84 (0.70) GPR84SLC22A6FFAR4ACE2FFAR1
SCHEMBL4195639 0.88 GPR84 (0.52) GPR84SLC22A6FFAR4FFAR1MAPT
SCHEMBL4206035 0.88 GPR84 (0.52) GPR84SLC22A6FFAR4FFAR1MAPT
SCHEMBL665787 0.88 GPR84 (0.52) GPR84SLC22A6FFAR4FFAR1MAPT
SCHEMBL4747859 0.88 GPR84 (0.52) GPR84SLC22A6FFAR4FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6093345-A PYRIMIDINE COMPOUNDS, ELECTROOPTICS TAKASAGO INTERNATIONAL CORPORATION (JP) 2000-07-25 US disclosed