SCHEMBL4206174

SCHEMBL4206174

O=[N+]([O-])/C(Br)=C/c1ccco1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 5/20 0.53
KMT2A Q03164 5/20 0.46
MEN1 O00255 4/20 0.46
MAPT P10636 4/20 0.46
TDP1 Q9NUW8 3/20 0.46
ALDH1A1 P00352 2/20 0.44
TSHR P16473 1/20 0.44
CYP2C19 P33261 1/20 0.44
POLB P06746 4/20 0.43
KDM4E B2RXH2 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
GAA P10253 1/20 0.41
THRB P10828 1/20 0.41
RECQL P46063 1/20 0.41
HCAR2 Q8TDS4 1/20 0.41
HSP90AA1 P07900 1/20 0.39
G6PD P11413 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4206177 1.00 FBP1 (0.53) FBP1KMT2AMEN1MAPTTDP1
SCHEMBL22528743 0.79 FBP1 (0.53) FBP1KMT2AMEN1MAPTTDP1
SCHEMBL4215748 0.79 FBP1 (0.53) FBP1KMT2AMEN1MAPTTDP1
SCHEMBL22528744 0.79 FBP1 (0.53) FBP1KMT2AMEN1MAPTTDP1
SCHEMBL4215747 0.79 FBP1 (0.53) FBP1KMT2AMEN1MAPTTDP1
SCHEMBL9341963 0.78 KMT2A (0.54) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL9341959 0.78 KMT2A (0.54) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL13904740 0.77 ALDH1A1 (0.47) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL14269855 0.76 POLB (0.47) KMT2AMEN1MAPTTDP1ALDH1A1
SCHEMBL11433280 0.76 POLB (0.47) KMT2AMEN1MAPTTDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186499-B2 Methods of inhibiting fouling in liquid systems ECOLAB USA INC. (US) 2021-11-30 US claimed
EP-2969972-B1 METHODS OF INHIBITING FOULING IN LIQUID SYSTEMS ECOLAB USA INC (US) 2020-03-25 EP claimed
US-20170036928-A1 Methods of Inhibiting Fouling in Liquid Systems ECOLAB USA INC. (US) 2017-02-09 US claimed
US-9505637-B2 Methods of inhibiting fouling in liquid systems ECOLAB USA INC. (US) 2016-11-29 US claimed
EP-1941877-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING NITROVINYLFURAN DERIVATIVES FOR THE TREATMENT OF LEISHMANIASIS AND TRYPANOSOMIASIS CT DE BIOACTIVOS QUIMICOS (CU) 2009-11-18 EP claimed
US-20090042978-A1 Pharmaceutical Compositions Containing Nitrovinylfuran Derivatives for the Treatment of Leishmaniosis and Trypanosomosis CENTRO DE BIOACTIVOS QUIMICOS (CU) 2009-02-12 US claimed
EP-1941877-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING NITROVINYLFURAN DERIVATIVES FOR THE TREATMENT OF LEISHMANIASIS AND TRYPANOSOMIASIS CENTRO DE BIOACTIVOS QUIMICOS (CU) 2008-07-09 EP claimed
EP-1480914-A1 METHOD FOR PREVENTING THE UNCONTROLLED GROWTH OF MICROORGANISMS IN WATER Beta Tec Hopfenprodukte Gmbh (DE) 2004-12-01 EP claimed
WO-2003074431-A1 METHOD FOR PREVENTING THE UNCONTROLLED GROWTH OF MICROORGANISMS IN WATER BETA TEC HOPFENPRODUKTE GMBH (DE) 2003-09-12 WO claimed
US-20020114856-A1 Compositions containing hops extract and their use in water systems and process streams to control biological fouling ONDEO NALCO COMPANY 2002-08-22 US claimed
EP-0382812-B1 A NEW INDUSTRIAL ANTIMICROBIAL: USES FOR 2-(2-BROMO-2-NITROETHENYL)-FURAN AND A NEW PROCESS OF FORMING 2-(2-BROMO-2-NITROETHENYL)-FURAN GREAT LAKES CHEMICAL CORP (US) 1993-11-03 EP claimed
EP-0561994-A1 PROCESS FOR THE PREPARATION OF 2-(2-BROMO-2-NITROETHENYL)FURAN. GREAT LAKES CHEMICAL CORP (US) 1993-09-29 EP claimed
US-5246963-A Bactericides, fungicides and algicides GREAT LAKES CHEMICAL CORP. (US) 1993-09-21 US claimed
US-5138076-A Reacting furfural with primary amine in a solvent to form schiffs base, removal of sovent and water formed, dissolving intermediate in polar solvent, reacting with bromonitromethane GREAT LAKES CHEMICAL CORPORATION (US) 1992-08-11 US claimed
US-5090990-A Bactericides, fungicides, algicides GREAT LAKES CHEMICAL CORPORATION (US) 1992-02-25 US claimed
US-5045104-A Bactericides, algicides, fungicides GREAT LAKES CHEMICAL CORPORATION (US) 1991-09-03 US claimed
EP-0382812-A4 A NEW INDUSTRIAL ANTIMICROBIAL: USES FOR 2-(2-BROMO-2-NITROETHENYL)-FURAN AND A NEW PROCESS OF FORMING 2-(2-BROMO-2-NITROETHENYL)-FURAN 1991-08-07 EP claimed
US-4965377-A REACTING FURFURAL WITH BROMOMETHYLMETHANE IN PRESENCE OF BASIC CATALYST GREAT LAKES CHEMICAL CORPORATION (US) 1990-10-23 US claimed
EP-0382812-A1 A NEW INDUSTRIAL ANTIMICROBIAL: USES FOR 2-(2-BROMO-2-NITROETHENYL)-FURAN AND A NEW PROCESS OF FORMING 2-(2-BROMO-2-NITROETHENYL)-FURAN. GREAT LAKES CHEMICAL CORP (US) 1990-08-22 EP claimed
WO-1989011793-A1 A NEW INDUSTRIAL ANTIMICROBIAL: USES FOR 2-(2-BROMO-2-NITROETHENYL)-FURAN AND A NEW PROCESS OF FORMING 2-(2-BROMO-2-NITROETHENYL)-FURAN GREAT LAKES CHEMICAL CORPORATION (US) 1989-12-14 WO claimed