Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203347 | 0.98 | POLB (0.40) | POLBALDH1A1MAPTTDP1EPHX2 | |
| SCHEMBL4194440 | 0.91 | ALDH1A1 (0.47) | POLBALDH1A1MAPTTDP1SLC6A1 | |
| SCHEMBL4206078 | 0.82 | ALDH1A1 (0.51) | POLBALDH1A1MAPTTDP1SLC6A1 | |
| SCHEMBL221946 | 0.77 | — | — | |
| SCHEMBL10000010 | 0.75 | ALDH1A1 (0.43) | POLBALDH1A1MAPTTDP1SLC6A1 | |
| SCHEMBL14679380 | 0.74 | EPHX1 (0.52) | POLBALDH1A1MAPTTDP1EPHX2 | |
| SCHEMBL5711897 | 0.74 | EPHX1 (0.52) | POLBALDH1A1MAPTTDP1EPHX2 | |
| SCHEMBL6946772 | 0.74 | EPHX1 (0.52) | POLBALDH1A1MAPTTDP1EPHX2 | |
| Water SCHEMBL15821272 | 0.74 | SLC6A12 (0.48) | POLBALDH1A1MAPTTDP1EPHX2 | |
| SCHEMBL175425 | 0.74 | EPHX1 (0.52) | POLBALDH1A1MAPTTDP1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090311303-A1 | BIODEGRADABLE IMPLANTS FOR BONE FUSION AND COMPOSITIONS THEREFOR | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2009-12-17 | — | — | US | disclosed |
| EP-2015789-A1 | BIODEGRADABLE IMPLANTS FOR BONE FUSION AND COMPOSITIONS THEREFOR | Queensland University of Technology (AU) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007124537-A1 | BIODEGRADABLE IMPLANTS FOR BONE FUSION AND COMPOSITIONS THEREFOR | QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) | 2007-11-08 | — | — | WO | disclosed |