Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15024826 | 0.84 | CYP1A2 (0.41) | ALDH1A1CYP1A2TP53LMNATSHR | |
| SCHEMBL4194440 | 0.82 | ALDH1A1 (0.47) | ALDH1A1POLBMAPTTDP1SLC6A1 | |
| SCHEMBL15024691 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10000025 | 0.79 | CYP1A2 (0.40) | ALDH1A1CYP1A2TP53LMNATSHR | |
| SCHEMBL363328 | 0.79 | CYP1A2 (0.42) | ALDH1A1CYP1A2TP53LMNATSHR | |
| SCHEMBL4206078 | 0.78 | ALDH1A1 (0.51) | ALDH1A1POLBMAPTTDP1SLC6A1 | |
| SCHEMBL10000021 | 0.77 | CYP1A2 (0.40) | ALDH1A1POLBCYP1A2TSHR | |
| SCHEMBL1365878 | 0.77 | HPGD (0.40) | ALDH1A1L3MBTL1 | |
| SCHEMBL336991 | 0.76 | ALDH1A1 (0.52) | ALDH1A1POLBMAPTTDP1SLC6A1 | |
| SCHEMBL3146225 | 0.76 | CYP1A2 (0.43) | ALDH1A1CYP1A2TP53LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267689-A1 | STIMULI-SWITCHABLE MOIETIES, MONOMERS AND POLYMERS INCORPORATING STIMULI-SWITCHABLE MOIETIES, AND METHODS OF MAKING AND USING SAME | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2017-09-21 | — | — | US | disclosed |
| US-20170267689-A1 | STIMULI-SWITCHABLE MOIETIES, MONOMERS AND POLYMERS INCORPORATING STIMULI-SWITCHABLE MOIETIES, AND METHODS OF MAKING AND USING SAME | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2017-09-21 | — | — | US | disclosed |
| WO-2016029307-A1 | STIMULI-SWITCHABLE MOIETIES, MONOMERS AND POLYMERS INCORPORATING STIMULI-SWITCHABLE MOIETIES, AND METHODS OF MAKING AND USING SAME | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-03-03 | — | — | WO | disclosed |
| US-8470958-B1 | Antibiotic-bound poly(caprolactone) polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-06-25 | — | — | US | disclosed |
| US-8470958-B1 | Antibiotic-bound poly(caprolactone) polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-06-25 | — | — | US | disclosed |
| US-20130150550-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130150550-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2013-06-13 | — | — | US | disclosed |
| US-8110678-B2 | Antibiotic-bound poly(caprolactone) polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-07 | — | — | US | disclosed |
| US-8110678-B2 | Antibiotic-bound poly(caprolactone) polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2012-02-07 | — | — | US | disclosed |
| WO-2007133706-A2 | ANTIBIOTIC-BOUND POLY (CAPROLACTONE) POLYMER | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-11-22 | — | — | WO | disclosed |
| US-20070265243-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-11-15 | — | — | US | disclosed |
| US-20070265243-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | UNIVERSITY OF SOUTH FLORIDA (US) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265243-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | CAPG, PGLS, GNE | ALDH1A1 2039/4885POLB 1729/4885MAPT 1680/4885 |
| US-20130150550-A1 | Antibiotic-Bound Poly(Caprolactone) Polymer | CAPG, PGLS, GNE | ALDH1A1 2039/4885POLB 1729/4885MAPT 1680/4885 |
| US-20170267689-A1 | STIMULI-SWITCHABLE MOIETIES, MONOMERS AND POLYMERS INCORPORATING STIMULI-SWITCHABLE MOIETIES, AND METHODS OF MAKING AND USING SAME | PASK, PAM, PTMS | ALDH1A1 4606/4885POLB 4768/4885MAPT 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.