SCHEMBL420634

SCHEMBL420634

COc1ccccc1C(C)(O)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.51
MEN1 O00255 3/20 0.51
ALDH1A1 P00352 2/20 0.50
GAA P10253 4/20 0.49
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA12 O43570 2/20 0.46
CA7 P43166 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 2/20 0.46
POLB P06746 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
HTT P42858 1/20 0.43
CASR P41180 1/20 0.43
PDK1 Q15118 1/20 0.43
PDK2 Q15119 1/20 0.43
PDK3 Q15120 1/20 0.43
PDK4 Q16654 1/20 0.43
CA4 P22748 1/20 0.43
ATM Q13315 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6404528 1.00 KMT2A (0.51) KMT2AMEN1ALDH1A1GAACA1
SCHEMBL17102000 0.83 KMT2A (0.49) KMT2AMEN1ALDH1A1GAACA1
SCHEMBL27785393 0.82 CTNNB1 (0.46) KMT2AMEN1ALDH1A1GAAPOLB
SCHEMBL11023514 0.80 KMT2A (0.47) KMT2AMEN1ALDH1A1GAACA1
SCHEMBL2795840 0.79 KMT2A (0.56) KMT2AMEN1ALDH1A1GAACA1
SCHEMBL9545821 0.78 ATM (0.37) KMT2AMEN1ALDH1A1GAAATM
SCHEMBL6436173 0.78 KMT2A (0.46) KMT2AMEN1ALDH1A1GAACA1
SCHEMBL29472193 0.78 CA1 (0.52) KMT2AMEN1ALDH1A1GAACA1
SCHEMBL9326049 0.78 CASR (0.57) KMT2AMEN1ALDH1A1GAACA1
SCHEMBL2951312 0.78 CA1 (0.52) KMT2AMEN1ALDH1A1GAACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230255989-A1 GLYCAN COMPOSITIONS AND USES THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2023-08-17 US disclosed
CN-115108901-A Synthetic method of alpha-hydroxycarboxylic acid compound 四川大学 2022-09-27 CN disclosed
US-11229660-B2 Glycan therapeutics and method of treating conditions associated with TMAO KALEIDO BIOSCIENCES, INC. (US) 2022-01-25 US disclosed
US-20210137956-A1 GLYCAN COMPOSITIONS AND USES THEREOF HERCULES CAPITAL, INC. 2021-05-13 US disclosed
US-20210113596-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2021-04-22 US disclosed
US-10881676-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2021-01-05 US disclosed
US-10702542-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2020-07-07 US disclosed
US-20200093851-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2020-03-26 US disclosed
US-20200093845-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2020-03-26 US disclosed
US-20190391092-A1 METABOLIC PROFILING WITH MAGNETIC RESONANCE MASS SPECTROMETRY (MRMS) Oregon Institute of Science and Medicine 2019-12-26 US disclosed
US-20170151268-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2017-06-01 US disclosed
US-20170151269-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF HERCULES CAPITAL, INC. 2017-06-01 US disclosed
US-9492473-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2016-11-15 US disclosed
US-20160213702-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2016-07-28 US disclosed
US-20120021061-A1 MEDICAL AND NUTRITIONAL FORMULATIONS COMVITA NEW ZEALAND LIMITED (NZ) 2012-01-26 US disclosed
US-20110287059-A1 HONEY ANALYSIS COMVITA NEW ZEALAND LIMITED (NZ) 2011-11-24 US disclosed
EP-2367444-A1 MEDICAL AND NUTRITIONAL FORMULATIONS Comvita New Zealand Limited (NZ) 2011-09-28 EP disclosed
EP-2368111-A1 HONEY ANALYSIS Comvita New Zealand Limited (NZ) 2011-09-28 EP disclosed
WO-2010082845-A1 HONEY ANALYSIS COMVITA NEW ZEALAND LIMITED (NZ) 2010-07-22 WO disclosed
WO-2010082846-A1 MEDICAL AND NUTRITIONAL FORMULATIONS COMVITA NEW ZEALAND LIMITED (NZ) 2010-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120021061-A1 MEDICAL AND NUTRITIONAL FORMULATIONS FABP6, NNT, IAPP KMT2A 3315/4885MEN1 276/4885ALDH1A1 2943/4885
US-20110287059-A1 HONEY ANALYSIS GLO1, GLMN, AGER KMT2A 1146/4885MEN1 1512/4885ALDH1A1 1337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.