Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28356576 | 0.96 | MAPT (0.55) | MAPTL3MBTL1SRD5A2RAB9AGAA | |
| SCHEMBL4189366 | 0.86 | NPC1 (0.53) | MAPTL3MBTL1SRD5A2RAB9AGAA | |
| SCHEMBL931177 | 0.85 | MAPT (0.57) | MAPTL3MBTL1SRD5A2RAB9AGAA | |
| SCHEMBL1351697 | 0.82 | L3MBTL1 (0.67) | MAPTL3MBTL1SRD5A2RAB9APLAU | |
| Bromobenzene SCHEMBL27979945 | 0.82 | MAPT (0.61) | MAPTL3MBTL1SRD5A2RAB9AGAA | |
| SCHEMBL2105216 | 0.81 | SMN1; SMN2 (0.62) | MAPTL3MBTL1RAB9AKDM4ENPC1 | |
| SCHEMBL24800 | 0.79 | MAPT (0.73) | MAPTL3MBTL1SRD5A2RAB9AGAA | |
| SCHEMBL7129800 | 0.79 | MAPT (0.80) | MAPTL3MBTL1SRD5A2RAB9AGAA | |
| SCHEMBL1515788 | 0.78 | MAPT (0.56) | MAPTL3MBTL1SRD5A2RAB9AGAA | |
| SCHEMBL570729 | 0.78 | EGFR (0.54) | MAPTL3MBTL1SRD5A2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626059-B2 | Multifunctional ethynyl substituted monomers and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2009-12-01 | — | — | US | disclosed |
| US-20090012193-A1 | Multifunctional Ethynyl Substituted Monomers and Polyarylene Compositions Therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2009-01-08 | — | — | US | disclosed |
| WO-2005037761-A2 | MULTIFUNCTIONAL ETHYNYL SUBSTITUTED MONOMERS AND POLYARYLENE COMPOSITIONS THEREFROM | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012193-A1 | Multifunctional Ethynyl Substituted Monomers and Polyarylene Compositions Therefrom | WEE2, WASF2, WEE1 | MAPT 4280/4885L3MBTL1 304/4885SRD5A2 3796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.