Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 3/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154944 | 0.76 | CTSK (0.35) | HDAC1GAACA1CA2CTSK | |
| SCHEMBL14748198 | 0.70 | CA1 (0.38) | HDAC1GAACA1CA2CTSK | |
| SCHEMBL13575237 | 0.70 | CA1 (0.38) | HDAC1GAACA1CA2CTSK | |
| SCHEMBL16871163 | 0.68 | HDAC4 (0.41) | EPHX1HDAC4HDAC1HDAC6GAA | |
| SCHEMBL31150301 | 0.68 | GAA (0.40) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL6117658 | 0.68 | AAK1 (0.36) | HDAC1GAACA1CA2CTSK | |
| SCHEMBL19176293 | 0.68 | CTSK (0.36) | HDAC1GAACA1CA2CTSK | |
| SCHEMBL12326431 | 0.68 | CTSK (0.36) | HDAC1GAACA1CA2CTSK | |
| SCHEMBL16867321 | 0.68 | METAP1 (0.36) | EPHX1PDK1PDK2PDK3PDK4 | |
| SCHEMBL16867320 | 0.67 | METAP1 (0.35) | PDK1PDK2PDK3PDK4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183413-B2 | Process for production of β-amino-α-hydroxy carboxamide derivative | KANEKA CORPORATION (JP) | 2012-05-22 | — | — | US | disclosed |
| US-20090312577-A1 | Process for Production of Beta-Amino-Alpha-Hydroxy Carbonxamide Derivative | KANEKA CORPORATION (JP) | 2009-12-17 | — | — | US | disclosed |
| EP-1988073-A1 | PROCESS FOR PRODUCTION OF BETA-AMINO-ALPHA-HYDROXY ACID AMIDE DERIVATIVE | Kaneka Corporation (JP) | 2008-11-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312577-A1 | Process for Production of Beta-Amino-Alpha-Hydroxy Carbonxamide Derivative | PTMA, ATIC, HCAR2 | EPHX1 2360/4885HDAC4 1731/4885HDAC1 1980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.