Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.60 |
| ▸ | MMP3 | P08254 | 9/20 | 0.60 |
| ▸ | MMP9 | P14780 | 9/20 | 0.60 |
| ▸ | MMP13 | P45452 | 9/20 | 0.60 |
| ▸ | MMP1 | P03956 | 5/20 | 0.60 |
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379164 | 1.00 | MMP2 (0.60) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL1841843 | 1.00 | MMP2 (0.60) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL1841540 | 0.94 | GPR139 (0.57) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL379512 | 0.94 | GPR139 (0.57) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL4216415 | 0.94 | GPR139 (0.57) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL1843457 | 0.91 | MMP2 (0.54) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL4205576 | 0.91 | MMP2 (0.54) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL5514590 | 0.91 | GPR139 (0.51) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL379424 | 0.91 | GPR139 (0.51) | MMP2MMP3MMP9MMP13MMP1 | |
| SCHEMBL1843935 | 0.91 | GPR139 (0.51) | MMP2MMP3MMP9MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | disclosed |