Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4112181 | 0.78 | KCNH2 (0.66) | KCNH2CYP19A1PDE4BALDH1A1HPGD | |
| SCHEMBL4112493 | 0.68 | PGR (0.42) | CYP19A1PDE4BALDH1A1HPGDMAOB | |
| SCHEMBL4106178 | 0.68 | KCNH2 (0.60) | KCNH2CYP19A1AR | |
| SCHEMBL4109289 | 0.66 | KCNH2 (0.58) | KCNH2AR | |
| SCHEMBL509689 | 0.62 | KCNH2 (0.79) | KCNH2 | |
| SCHEMBL4581525 | 0.62 | CYP19A1 (0.65) | CYP19A1PDE4BALDH1A1HPGDMAOB | |
| SCHEMBL29390509 | 0.62 | CYP19A1 (0.65) | CYP19A1PDE4BALDH1A1HPGDMAOB | |
| SCHEMBL4141536 | 0.62 | AR (0.51) | CYP19A1PDE4BALDH1A1HPGDMAOB | |
| SCHEMBL4109180 | 0.62 | KCNH2 (0.75) | KCNH2CYP19A1 | |
| SCHEMBL4104698 | 0.61 | AR (0.43) | CYP19A1PDE4BALDH1A1HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7482375-B2 | Compounds useful in therapy | PFIZER INC. (US) | 2009-01-27 | — | — | US | disclosed |