Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 16/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4212678 | 0.87 | KISS1R (0.56) | KISS1R | |
| SCHEMBL4207862 | 0.87 | KISS1R (0.46) | KISS1R | |
| SCHEMBL4211555 | 0.87 | KISS1R (0.45) | KISS1R | |
| SCHEMBL4199533 | 0.81 | KISS1R (0.41) | KISS1R | |
| SCHEMBL5023364 | 0.81 | IKBKB (0.48) | IKBKBCHUKKISS1R | |
| SCHEMBL4215090 | 0.80 | KISS1R (0.49) | KISS1R | |
| SCHEMBL4209131 | 0.80 | KISS1R (0.45) | IKBKBKISS1R | |
| SCHEMBL4210537 | 0.78 | IKBKB (0.57) | IKBKBCHUKKISS1R | |
| SCHEMBL4210782 | 0.78 | IKBKB (0.46) | IKBKBCHUKKISS1R | |
| SCHEMBL4202079 | 0.75 | IKBKB (0.47) | IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | GNRHR, PGR, MC1R | IKBKB 1068/4885CHUK 915/4885KISS1R 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.