Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4209128 | 0.93 | KISS1R (0.44) | KISS1RSIRT2 | |
| SCHEMBL5014023 | 0.93 | KISS1R (0.47) | KISS1R | |
| SCHEMBL4207860 | 0.90 | KISS1R (0.49) | KISS1R | |
| SCHEMBL4212677 | 0.88 | KISS1R (0.59) | KISS1R | |
| SCHEMBL4210782 | 0.87 | IKBKB (0.46) | KISS1RSIRT2 | |
| SCHEMBL5014016 | 0.86 | KISS1R (0.47) | KISS1R | |
| SCHEMBL4199530 | 0.83 | KISS1R (0.43) | KISS1RSIRT2 | |
| SCHEMBL5014960 | 0.82 | KISS1R (0.51) | KISS1R | |
| SCHEMBL4215089 | 0.82 | KISS1R (0.51) | KISS1R | |
| SCHEMBL5015005 | 0.81 | KISS1R (0.62) | KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | GNRHR, PGR, MC1R | KISS1R 16/4885SIRT2 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.