Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18287419 | 0.94 | TSHR (0.44) | TSHRLMNAPAMNFKB1PMP22 | |
| SCHEMBL11242735 | 0.91 | PAM (0.61) | TSHRPAMAKR1B1ALDH1A1GPR84 | |
| SCHEMBL230981 | 0.90 | TSHR (0.44) | TSHRLMNAPAMNFKB1PMP22 | |
| SCHEMBL8594577 | 0.89 | PAM (0.44) | TSHRLMNAPAMNFKB1PMP22 | |
| SCHEMBL8522424 | 0.89 | PAM (0.44) | TSHRLMNAPAMNFKB1PMP22 | |
| Ethylene SCHEMBL30631590 | 0.88 | TSHR (0.45) | TSHRLMNAPAMNFKB1PMP22 | |
| SCHEMBL852014 | 0.88 | TSHR (0.48) | TSHRLMNAPAMNFKB1PMP22 | |
| SCHEMBL29772194 | 0.87 | TSHR (0.42) | TSHRPAMAKR1B1ALDH1A1GPR84 | |
| SCHEMBL7560959 | 0.87 | KDM4C (0.45) | TSHRLMNAPAMNFKB1PMP22 | |
| SCHEMBL1172670 | 0.87 | TSHR (0.38) | TSHRLMNAPAMNFKB1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090061172-A1 | Polyurethane Resin Composition for Durable Moisture-Permeable Waterproof Sheet, Moisture-Permeable Waterproof Sheet and Method of Manufacturing the Same | KOMATSU SEIREN CO., LTD. (JP) | 2009-03-05 | — | — | US | disclosed |
| CN-1137213-C | Structural material, molding made therefrom, and method of degradation of these | ���µ�����ҵ��ʽ���� | 2004-02-04 | — | — | CN | disclosed |
| CN-1161051-A | Structural material, molding made therefrom, and method of degradation of these | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1997-10-01 | — | — | CN | disclosed |