Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.45 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1235404 | 0.94 | MAPT (0.42) | KDM4CKDM4APHF8KDM2APAM | |
| SCHEMBL29361777 | 0.94 | MAPT (0.42) | KDM4CKDM4APHF8KDM2APAM | |
| SCHEMBL2129736 | 0.92 | MAPT (0.40) | KDM4CKDM4APHF8KDM2APAM | |
| SCHEMBL26474473 | 0.88 | DGKA (0.43) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL4211949 | 0.87 | TSHR (0.48) | PAMFFAR4FFAR1ALDH1A1TSHR | |
| SCHEMBL11104131 | 0.86 | MAPT (0.39) | KDM4CKDM4APHF8KDM2APAM | |
| SCHEMBL29926571 | 0.86 | MAPT (0.39) | KDM4CKDM4APHF8KDM2APAM | |
| SCHEMBL5180686 | 0.84 | MAPT (0.37) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL17581573 | 0.83 | MAPT (0.42) | KDM4CKDM4APHF8KDM2APAM | |
| SCHEMBL17581563 | 0.83 | MAPT (0.42) | KDM4CKDM4APHF8KDM2APAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646638-B1 | Lubricants containing carboxylic esters | LUBRIZOL CORP (US) | 2002-07-17 | — | — | EP | disclosed |
| US-5733853-A | Lubricants containing carboxylic esters from polyhydroxy compounds, suitable for ceramic containing engines | THE LUBRIZOL CORPORATION (US) | 1998-03-31 | — | — | US | disclosed |
| US-5458794-A | Internal combustion engines | THE LUBRIZOL CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |