Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21143855 | 0.88 | ADORA2A (0.64) | KMT2AALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL31127200 | 0.88 | ADORA2A (0.64) | KMT2AALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL13326955 | 0.83 | KMT2A (1.00) | KMT2AMAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL4219242 | 0.82 | MAPT (1.00) | KMT2AALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL4207871 | 0.82 | ALOX15 (1.00) | KMT2AALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL12918499 | 0.81 | KMT2A (0.67) | KMT2AALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL4207277 | 0.80 | SMN1; SMN2 (0.66) | KMT2AALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL2447803 | 0.79 | ADORA2A (0.66) | MAPTSMN1; SMN2LMNAADORA2AADORA1 | |
| SCHEMBL21144053 | 0.79 | SMN1; SMN2 (0.64) | KMT2AALOX15MAPTSMN1; SMN2LMNA | |
| SCHEMBL19686779 | 0.78 | ADORA2A (0.64) | ALOX15MAPTSMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563552-B2 | Whitening agent and skin external preparation | SHISEIDO COMPANY LTD. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-8563552-B2 | Whitening agent and skin external preparation | SHISEIDO COMPANY LTD. (JP) | 2013-10-22 | — | — | US | disclosed |
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | SHISEIDO COMPANY LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
| US-20090036475-A1 | Pyrazolyl-Pyrimidines as Potassium Channel Modulating Agents and Their Medical Use | NEUROSEARCH A/S (DK) | 2009-02-05 | — | — | US | disclosed |
| EP-1863796-A1 | PYRAZOLYL-PYRIMIDINES AS POTASSIUM CHANNEL MODULATING AGENTS AND THEIR MEDICAL USE | NeuroSearch A/S (DK) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006100212-A1 | PYRAZOLYL-PYRIMIDINES AS POTASSIUM CHANNEL MODULATING AGENTS AND THEIR MEDICAL USE | NEUROSEARCH A/S (DK) | 2006-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003817-A1 | Whitening Agent And Skin External Preparation | TYR, MC1R, RTN3 | KMT2A 2730/4885ALOX15 510/4885MAPT 4460/4885 |
| US-20090036475-A1 | Pyrazolyl-Pyrimidines as Potassium Channel Modulating Agents and Their Medical Use | KCND2, KCNJ2, KCNN3 | KMT2A 2246/4885ALOX15 4049/4885MAPT 1140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.