Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | LIG1 | P18858 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19808987 | 0.78 | LMNA (0.38) | SLC6A2HTR2AHTR2CSLC6A4HTR2B | |
| SCHEMBL19119387 | 0.76 | HTR2A (0.42) | KDM1ASLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL1066184 | 0.65 | KDM1A (0.48) | KDM1AATMSLC6A2HTR2AHTR2C | |
| SCHEMBL18161913 | 0.65 | KDM1A (0.48) | KDM1AATMSLC6A2HTR2AHTR2C | |
| SCHEMBL353495 | 0.62 | ESR2 (0.47) | KDM1AATM | |
| SCHEMBL4038924 | 0.62 | KDM1A (0.44) | KDM1AATMSLC6A2HTR2AHTR2C | |
| SCHEMBL937356 | 0.62 | TSHR (0.56) | KDM1AATMSLC6A2HTR2AHTR2C | |
| SCHEMBL2114415 | 0.62 | KDM1A (0.44) | KDM1AATMSLC6A2HTR2AHTR2C | |
| SCHEMBL779666 | 0.62 | ATM (0.46) | KDM1AATMSLC6A2HTR2AHTR2C | |
| SCHEMBL4766149 | 0.62 | KDM1A (0.39) | KDM1AATMSLC6A2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2200440-B1 | ANTIBACTERIAL AMIDE AND SULFONAMIDE SUBSTITUTED HETEROCYCLIC UREA COMPOUNDS | CRESTONE INC (US) | 2017-07-19 | — | — | EP | claimed |
| EP-1436291-B1 | INDOLIZINES AS KINASE PROTEIN INHIBITORS | AVENTIS PHARMA SA (FR) | 2009-01-14 | — | — | EP | claimed |