Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.73 |
| ▸ | PKM | P14618 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984728 | 0.92 | DNMT1 (0.75) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL3081901 | 0.92 | DNMT1 (0.75) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL2445932 | 0.92 | DNMT1 (0.75) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL19244073 | 0.91 | DNMT1 (0.73) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL2443777 | 0.91 | DNMT1 (0.73) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| Tryptophan SCHEMBL8845198 | 0.86 | KMT2A (0.71) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL23683013 | 0.86 | DNMT1 (1.00) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL5291841 | 0.86 | DNMT1 (1.00) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL5291835 | 0.86 | DNMT1 (1.00) | DNMT1KMT2ACYP2C19DNMT3BPKM | |
| SCHEMBL30167914 | 0.85 | KMT2A (1.00) | DNMT1KMT2ACYP2C19DNMT3BPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090028796-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090028796-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | IDO1, IDO2, INMT | DNMT1 3057/4885KMT2A 3257/4885CYP2C19 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.