Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | PKM | P14618 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | STAT3 | P40763 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | MPO | P05164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984728 | 1.00 | DNMT1 (0.75) | DNMT1KMT2APKMCYP2C19DNMT3B | |
| SCHEMBL2445932 | 1.00 | DNMT1 (0.75) | DNMT1KMT2APKMCYP2C19DNMT3B | |
| SCHEMBL19244073 | 0.96 | DNMT1 (0.73) | DNMT1KMT2APKMCYP2C19DNMT3B | |
| SCHEMBL2443777 | 0.96 | DNMT1 (0.73) | DNMT1KMT2APKMCYP2C19DNMT3B | |
| Tryptophan SCHEMBL8845198 | 0.93 | KMT2A (0.71) | DNMT1KMT2APKMCYP2C19DNMT3B | |
| SCHEMBL4214992 | 0.92 | DNMT1 (0.75) | DNMT1KMT2APKMCYP2C19DNMT3B | |
| SCHEMBL3089375 | 0.88 | DNMT1 (0.58) | DNMT1KMT2APKMCYP2C19DNMT3B | |
| SCHEMBL3080269 | 0.88 | DNMT1 (0.58) | DNMT1KMT2APKMCYP2C19DNMT3B | |
| Potassium Ion SCHEMBL2438113 | 0.88 | DNMT1 (0.58) | DNMT1KMT2APKMCYP2C19DNMT3B | |
| SCHEMBL23683013 | 0.86 | DNMT1 (1.00) | DNMT1KMT2APKMCYP2C19DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905763-B1 | N-ACYLIC AMINOACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS | NEBOLSIN VLADIMIR EVGENIEVICH (RU) | 2019-05-08 | — | — | EP | claimed |
| US-8940780-B2 | N-acylic aminoacid derivatives, method for the production thereof, pharmacological composition and the use in the form anti-allergic, anti-inflammatory and hypolipidemic agents | OTKRYTOE AKTSIONERNOE OBSCHESTVO OTECHESTVENNYE LEKARSTVA (RU) | 2015-01-27 | — | — | US | claimed |
| US-20080319040-A1 | N-Acylic Aminoacid Derivatives, Method For The Production Thereof, Pharmacological Composition And The Use In The Form Anti-Allergic, Anti-Inflammatory And Hypolipidemic Agents | OTKRYTOE AKTSIONERNOE OBSCHESTVO "OTECHESTVENNYE LEKARSTVA (RU) | 2008-12-25 | — | — | US | claimed |
| EP-1905763-A1 | N-ACYLIC AMINOACID DERIVATIVES. METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS | Nebolsin, Vladimir Evgenievich (RU) | 2008-04-02 | — | — | EP | claimed |
| EP-1905763-B1 | N-ACYLIC AMINOACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS | NEBOLSIN VLADIMIR EVGENIEVICH (RU) | 2019-05-08 | — | — | EP | disclosed |
| US-8940780-B2 | N-acylic aminoacid derivatives, method for the production thereof, pharmacological composition and the use in the form anti-allergic, anti-inflammatory and hypolipidemic agents | OTKRYTOE AKTSIONERNOE OBSCHESTVO OTECHESTVENNYE LEKARSTVA (RU) | 2015-01-27 | — | — | US | disclosed |
| US-8318950-B2 | N-acyl amino acid derivatives, a method for the preparation thereof, a pharmaceutical composition and use thereof as anti-allergic, anti-inflammatory and hypolipidemic agents | Otkrytoe Aktsionernoe Obschestvo-Otechestvennye Lekarstva (RU) | 2012-11-27 | — | — | US | disclosed |
| US-20100267962-A1 | N-ACYLIC AMINOACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS | Nebolsin, Vladimir Evgenievich (RU) | 2010-10-21 | — | — | US | disclosed |
| US-20080319040-A1 | N-Acylic Aminoacid Derivatives, Method For The Production Thereof, Pharmacological Composition And The Use In The Form Anti-Allergic, Anti-Inflammatory And Hypolipidemic Agents | OTKRYTOE AKTSIONERNOE OBSCHESTVO "OTECHESTVENNYE LEKARSTVA (RU) | 2008-12-25 | — | — | US | disclosed |
| EP-1905763-A1 | N-ACYLIC AMINOACID DERIVATIVES. METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS | Nebolsin, Vladimir Evgenievich (RU) | 2008-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267962-A1 | N-ACYLIC AMINOACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS | HRH4, HRH2, AADAT | DNMT1 4804/4885KMT2A 1759/4885PKM 4226/4885 |
| US-20080319040-A1 | N-Acylic Aminoacid Derivatives, Method For The Production Thereof, Pharmacological Composition And The Use In The Form Anti-Allergic, Anti-Inflammatory And Hypolipidemic Agents | HRH4, HRH2, AADAT | DNMT1 4804/4885KMT2A 1759/4885PKM 4226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.