Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 2/20 | 0.49 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4219751 | 0.98 | ERBB2 (0.50) | ERBB2CHUKADORA2AADORA1TSHR | |
| SCHEMBL22004673 | 0.80 | ERBB2 (0.53) | ERBB2KDM5AALDH1A1KDM4ELMNA | |
| SCHEMBL28241531 | 0.80 | ERBB2 (0.53) | ERBB2ADORA2AADORA1KDM5AMCL1 | |
| SCHEMBL19897377 | 0.74 | KDM5A (0.43) | KDM5AALDH1A1KDM4E | |
| SCHEMBL11937878 | 0.74 | LRRK2 (0.46) | ADORA2AADORA1ALDH1A1 | |
| SCHEMBL4282428 | 0.74 | MAOB (0.46) | ERBB2ADORA1TSHRGRM5 | |
| SCHEMBL8884581 | 0.74 | LRRK2 (0.47) | ALDH1A1KDM4EHPGD | |
| SCHEMBL29024294 | 0.74 | VCAM1 (0.43) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL23719266 | 0.73 | ERBB2 (0.43) | ERBB2CHUKADORA2AADORA1KDM5A | |
| SCHEMBL15756593 | 0.73 | POLB (0.42) | ERBB2ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2009227602-A | CYANOPHENYLPYRAZOLE IRIDIUM COMPLEX, LUMINESCENT MATERIAL CONSISTING OF THE SAME AND ORGANIC EL ELEMENT CONTAINING THE SAME | CHEMIPROKASEI KAISHA LTD | 2009-10-08 | — | — | JP | disclosed |