Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 6/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 14/20 | 0.48 |
| ▸ | PGR | P06401 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814256 | 0.83 | NR3C1 (0.52) | NR3C1PGR | |
| SCHEMBL4330705 | 0.82 | NR3C1 (0.49) | NR3C1PGR | |
| SCHEMBL833894 | 0.81 | NR3C1 (0.72) | NR3C1PGR | |
| SCHEMBL833895 | 0.81 | NR3C1 (0.72) | NR3C1PGR | |
| SCHEMBL12805643 | 0.75 | NR3C1 (0.56) | NR3C1PGR | |
| SCHEMBL4456539 | 0.74 | NR3C1 (0.52) | NR3C1PGR | |
| SCHEMBL12805049 | 0.72 | NR3C1 (0.59) | NR3C1PGR | |
| SCHEMBL4222836 | 0.71 | NR3C1 (0.54) | NR3C1PGR | |
| SCHEMBL9943265 | 0.70 | NR3C1 (0.50) | NR3C1PGR | |
| SCHEMBL4327025 | 0.70 | NR3C1 (0.55) | NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009142568-A1 | COMBINATION OF (A) GLUCOCORTICOID RECEPTOR MODULATOR AND (B) A B2-AGONIST | ASTRAZENECA AB (SE) | 2009-11-26 | — | — | WO | disclosed |