SCHEMBL421787

SCHEMBL421787

COC(=O)[C@H](C)N(C(=O)[C@@H](N)CC(=O)O)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.42
MEN1 O00255 2/20 0.42
PLA2G1B P04054 1/20 0.42
HTT P42858 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
LTA4H P09960 3/20 0.42
ALDH1A1 P00352 2/20 0.39
LMNA P02545 2/20 0.39
TP53 P04637 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ESRRB O95718 1/20 0.38
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
KIF11 P52732 1/20 0.36
MAPT P10636 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23923952 1.00 KMT2A (0.42) KMT2AMEN1PLA2G1BHTTNPSR1
SCHEMBL10533268 0.91 KCNA5 (0.42) KMT2AMEN1PLA2G1BHTTNPSR1
SCHEMBL9514133 0.88 MEN1 (0.43) KMT2AMEN1ALDH1A1LMNATP53
Aspartame SCHEMBL2107955 0.86 ALDH1A1 (0.52) ALDH1A1LMNA
SCHEMBL6690977 0.86 ALDH1A1 (0.43) LTA4HALDH1A1LMNATP53SMN1; SMN2
SCHEMBL1434038 0.86 ALDH1A1 (0.43) LTA4HALDH1A1LMNATP53SMN1; SMN2
SCHEMBL11235723 0.84 CASP1 (0.38) ALDH1A1LMNATP53SMN1; SMN2
SCHEMBL11122333 0.82 KMT2A (0.39) KMT2AMEN1PLA2G1BHTTNPSR1
SCHEMBL7537846 0.81 KMT2A (0.36) KMT2AMEN1PLA2G1BHTTNPSR1
SCHEMBL10743692 0.81 KMT2A (0.42) KMT2AMEN1PLA2G1BHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 550 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3562511-B1 RNAI THERAPIES FOR CEREBRAL ISCHEMIA VIVIBABA INC (US) 2025-08-06 EP claimed
CN-120078958-A Biophysical and biochemical dual-gradient bionic hydrogel, preparation and application thereof in promoting bone cartilage regeneration 北京大学国际医院 2025-06-03 CN claimed
CN-120053623-A Tumor nano vaccine and preparation method thereof 上海巴久巴生物技术有限公司 2025-05-30 CN claimed
WO-2025073250-A1 LACTATE OXIDASE NANOCAPSULE AND PREPARATION METHOD THEREFOR 张铭 2025-04-10 WO claimed
CN-110869056-B RNAi treatment of cerebral ischemia 维维巴巴公司 2025-01-07 CN claimed
US-20230125099-A1 ORONASAL CBD FORMULATIONS AND USES THEREOF JUPITER WELLNESS INC (US) 2023-04-27 US claimed
US-20230033849-A1 CBD SUNSCREEN FORMULATIONS AND USES THEREOF JUPITER WELLNESS INC (US) 2023-02-02 US claimed
US-20230026847-A1 CBD FORMULATIONS AND USES THEREOF Jupiter Wellness, Inc. 2023-01-26 US claimed
CN-115478066-A Preparation of mesoporous silica microcapsule for immobilization optimization based on steric hindrance 北京化工大学 2022-12-16 CN claimed
CN-115151241-A CBD formulations and uses thereof 朱庇特健康公司 2022-10-04 CN claimed
EP-0256515-B1 Process for producing dry alpha-L-aspartyl-L-phenylalanine methyl ester HOLLAND SWEETENER CO (NL) 1995-03-29 EP claimed
WO-1995001156-A1 BREATH PROTECTION MICROCAPSULES THE PROCTER & GAMBLE COMPANY (US) 1995-01-12 WO claimed
US-5370864-A With core containing cetylphridinium chloride, acesulfame, additional artificial sweetener THE PROCTER & GAMBLE COMPANY (US) 1994-12-06 US claimed
US-5041607-A Sweeteners obtained by cooling solution through conductive heat transfer AJINOMOTO CO., INC. (JP) 1991-08-20 US claimed
US-4874606-A FLAVORED AND SWEETENED BEVERAGE CONTAINING WATER, SODIUM CHLORIDE, CITRATE AND METHYL ASPARTYLPHENYLALANINE TO PROMOTE EMPTYING OF STOMACH GENERAL FOODS CORP. (US) 1989-10-17 US claimed
EP-0126570-B1 A POWDER FILLED CHEWING GUM PIECE WARNER-LAMBERT COMPANY (US) 1988-08-03 EP claimed
EP-0102032-B1 STABILIZED ASPARTAME COMPOSITIONS AJINOMOTO CO., INC. (JP) 1986-12-17 EP claimed
US-4513012-A Powdered center-filled chewing gum compositions WARNER-LAMBERT COMPANY (US) 1985-04-23 US claimed
EP-0126570-A2 A powder filled chewing gum piece WARNER-LAMBERT COMPANY (US) 1984-11-28 EP claimed
US-4158068-A Sweetener mixture HOECHST AKTIENGESELLSCHAFT (DE) 1979-06-12 US claimed