Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4225500 | 0.89 | ACKR3 (0.42) | ACKR3KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL4221350 | 0.87 | CCR3 (0.43) | KMT2AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4221347 | 0.87 | CCR3 (0.43) | KMT2AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4218076 | 0.84 | GRIN2B (0.35) | KMT2AALDH1A1MEN1GRIN2BRXRB | |
| SCHEMBL4216333 | 0.74 | ALDH1A1 (0.48) | KMT2AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4216323 | 0.74 | ALDH1A1 (0.48) | KMT2AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4225493 | 0.71 | GRIN2B (0.35) | KMT2AALDH1A1MEN1KCNH2GRIN2B | |
| SCHEMBL4220805 | 0.70 | CCR3 (0.52) | KMT2AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4220809 | 0.70 | CCR3 (0.52) | KMT2AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1810027 | 0.69 | HPGD (0.46) | ACKR3KMT2AALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090118288-A1 | N-Benzyl-Morpholine Derivatives as Modulators of the Chemokine Receptor | ASTRAZENECA AB (SE) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118288-A1 | N-Benzyl-Morpholine Derivatives as Modulators of the Chemokine Receptor | CCR3, CCR1, CCR5 | ACKR3 7/4885KMT2A 4599/4885ALDH1A1 3009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.