SCHEMBL4219005

SCHEMBL4219005

COC(=O)C(=O)N1CCC[C@H]1C(=O)NNC(=O)OCc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 1/20 0.71
NPSR1 Q6W5P4 1/20 0.54
ALDH1A1 P00352 2/20 0.52
TSHR P16473 2/20 0.51
KMT2A Q03164 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
KDM4E B2RXH2 1/20 0.51
LMNA P02545 1/20 0.51
TP53 P04637 1/20 0.51
MEN1 O00255 1/20 0.51
GFER P55789 1/20 0.50
CTSK P43235 1/20 0.50
CTRB1 P17538 1/20 0.50
CYP3A4 P08684 1/20 0.49
PREP P48147 3/20 0.49
PRCP P42785 1/20 0.48
HSD17B10 Q99714 1/20 0.48
ACE P12821 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4219015 1.00 FKBP1A (0.71) FKBP1ANPSR1ALDH1A1TSHRKMT2A
SCHEMBL4654345 0.91 FKBP1A (0.57) FKBP1ANPSR1ALDH1A1TSHRKMT2A
SCHEMBL4654349 0.91 FKBP1A (0.57) FKBP1ANPSR1ALDH1A1TSHRKMT2A
SCHEMBL4229783 0.89 FKBP1A (0.57) FKBP1ANPSR1ALDH1A1TSHRKMT2A
SCHEMBL4229779 0.89 FKBP1A (0.57) FKBP1ANPSR1ALDH1A1TSHRKMT2A
SCHEMBL16611343 0.87 CTRB1 (0.54) FKBP1ANPSR1ALDH1A1TSHRKMT2A
SCHEMBL19920598 0.86 FKBP1A (0.93) FKBP1ANPSR1ALDH1A1TSHRCYP3A4
SCHEMBL4228978 0.85 KMT2A (0.59) FKBP1ANPSR1ALDH1A1TSHRKMT2A
SCHEMBL4228972 0.85 KMT2A (0.59) FKBP1ANPSR1ALDH1A1TSHRKMT2A
SCHEMBL21423119 0.82 FKBP1A (0.78) FKBP1ANPSR1ALDH1A1TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090105091-A1 Modified Amino Acids TECHNISCHE UNIVERSITAT WIEN (AT) 2009-04-23 US disclosed
EP-1989180-A1 MODIFIED AMINO ACIDS Technische Universität Wien (AT) 2008-11-12 EP disclosed
WO-2007095980-A1 MODIFIED AMINO ACIDS TECHNISCHE UNIVERSITÄT WIEN (AT) 2007-08-30 WO disclosed
EP-1826199-A1 Modified amino acids Technische Universität Wien (AT) 2007-08-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090105091-A1 Modified Amino Acids SLC1A2, NR1H4, OXGR1 FKBP1A 191/4885NPSR1 214/4885ALDH1A1 1588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.