SCHEMBL422

SCHEMBL422

O=C(Cl)c1ccccc1C(=O)Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.67
ALOX15 P16050 2/20 0.67
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
POLB P06746 2/20 0.44
KDM4E B2RXH2 4/20 0.43
HPGD P15428 3/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
HMGB1 P09429 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
CA14 Q9ULX7 1/20 0.43
TSHR P16473 4/20 0.42
MAPT P10636 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28422933 0.97 ALDH1A1 (0.64) ALDH1A1ALOX15CES2CES1POLB
Hydrochloric Acid SCHEMBL28325289 0.97 ALDH1A1 (0.64) ALDH1A1ALOX15CES2CES1POLB
Cyclohexane SCHEMBL28429706 0.91 ALDH1A1 (0.58) ALDH1A1ALOX15CES2CES1POLB
SCHEMBL9375700 0.91 ALDH1A1 (0.58) ALDH1A1ALOX15CES2CES1POLB
SCHEMBL696197 0.89 ALDH1A1 (0.74) ALDH1A1ALOX15POLBKDM4EHPGD
SCHEMBL237838 0.87 ALDH1A1 (0.54) ALDH1A1ALOX15CES2CES1POLB
SCHEMBL9126690 0.87 ALDH1A1 (0.54) ALDH1A1ALOX15CES2CES1POLB
SCHEMBL17715391 0.87 ALDH1A1 (0.54) ALDH1A1ALOX15CES2CES1POLB
SCHEMBL7833007 0.87 ALDH1A1 (0.56) ALDH1A1ALOX15CES2CES1POLB
Phenol SCHEMBL28883584 0.87 CA12 (0.55) ALDH1A1ALOX15CES2CES1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9446 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636622-B2 Preparation method of reverse osmosis composite membrane and reverse osmosis composite membrane prepared thereby Hunan Ovay Film Technology Co., Ltd. (CN) 2026-05-26 US claimed
CN-115532062-B Enhanced chlorine-resistant reverse osmosis membrane and preparation method thereof Hunan Aowui Membrane Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122080606-A Allyl polyarylester modified bismaleimide resin and preparation method and application thereof 2026-05-26 CN claimed
WO-2026102596-A1 POLYAMIDE COMPOSITE FILM AND PREPARATION METHOD THEREFOR 苏州苏瑞膜纳米科技集团有限公司 2026-05-21 WO claimed
CN-115845639-B Nanofiltration membrane containing molecular sieve organic composite material intermediate layer and preparation method thereof 福建省金皇环保科技股份有限公司 2026-05-19 CN claimed
WO-2026099847-A1 SYNTHESIS OF CYANO-ANTHRANILIC ACID ADAMA MAKHTESHIM LTD. (IL) 2026-05-15 WO claimed
CN-122006522-A High-flux high-salt polyamide nanofiltration membrane and preparation method thereof 杭州水处理技术研究开发中心有限公司 2026-05-12 CN claimed
CN-122006501-A Bionic strong acid-resistant nanofiltration membrane and preparation method thereof 杭州水处理技术研究开发中心有限公司 2026-05-12 CN claimed
CN-119971784-B Preparation method of nanofiltration membrane with high pollution resistance 华东理工大学 2026-05-12 CN claimed
CN-122025770-A Tough solid polymer electrolyte membrane and preparation method and application thereof 中山大学 2026-05-12 CN claimed
US-4277576-A Preparation of modified polymers of N-vinylpyrrolid-2-one and their use for the preparation of polymers interrupted by bridge members BASF AKTIENGESELLSCHAFT (DE) 1981-07-07 US claimed
US-4165337-A HALOACYLATION OF HEXACHLOROXYLENES MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1979-08-21 US claimed
US-4122115-A FROM THE ACETIC ACID AND CHLOROSULFONIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-10-24 US claimed
US-4068676-A RELEASE AGENTS HALLIBURTON COMPANY (US) 1978-01-17 US claimed
US-4056550-A FROM LACTONITRILE AND PHTHALOYL HALIDE GENERAL ELECTRIC COMPANY (US) 1977-11-01 US claimed
US-4025580-A ACYLATION IN PRESENCE OF LEWIS ACID CATALYST; BIODEGRADABLE PACKAGING OWENS-ILLINOIS, INC. (US) 1977-05-24 US claimed
US-4016153-A Monoazo dyestuff mixtures derived from 2-amino-5-nitro-thiazole and bis-hydroxyalkylamino acklanilides reacted with acid halides and amides AMERICAN COLOR & CHEMICAL CORPORATION (US) 1977-04-05 US claimed
US-4008212-A Monoazo dye mixtures derived from 7-amino-4-nitrobenzotriazole and bis-hydroxyalkylamino acylanilides reacted with acid halides and amides AMERICAN COLOR & CHEMICAL CORPORATION (US) 1977-02-15 US claimed
US-3951888-A Process for preparing polyoxyalkylene having allyl end-group KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1976-04-20 US claimed
US-3947443-A Process for preparing 1,3-bis(halomethyl)phenobarbitals THE KENDALL COMPANY (US) 1976-03-30 US claimed