SCHEMBL422010

SCHEMBL422010

O=S(=O)(Cc1ccc(F)cc1)Cc1ccc(F)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.51
LMNA P02545 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
KMT2A Q03164 2/20 0.47
IDO1 P14902 2/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
TP53 P04637 1/20 0.45
MAPT P10636 1/20 0.43
TAAR1 Q96RJ0 1/20 0.42
EGFR P00533 1/20 0.41
ERBB2 P04626 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
FAAH O00519 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
ELANE P08246 1/20 0.41
PRTN3 P24158 1/20 0.41
PRSS3 P35030 1/20 0.41
AGXT P21549 1/20 0.41
MEN1 O00255 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL775451 0.88 LMNA (0.44) USP2LMNANPSR1KMT2AIDO1
SCHEMBL15568647 0.83 USP2 (0.44) USP2LMNANPSR1KMT2AIDO1
SCHEMBL14426959 0.83 KMT2A (0.43) USP2LMNANPSR1KMT2ATP53
SCHEMBL776591 0.83 USP2 (0.41) USP2LMNANPSR1KMT2AIDO1
SCHEMBL9421733 0.82 FAAH (0.62) USP2LMNANPSR1KMT2AIDO1
SCHEMBL24188595 0.81 SMN1; SMN2 (0.41) USP2LMNANPSR1KMT2AIDO1
SCHEMBL1137128 0.81 LMNA (0.47) USP2LMNANPSR1KMT2ATP53
SCHEMBL777188 0.80 KMT2A (0.44) LMNAKMT2AIDO1LOXL2TAAR1
SCHEMBL486977 0.80 KMT2A (0.44) USP2LMNANPSR1KMT2AIDO1
SCHEMBL1259830 0.80 KMT2A (0.44) USP2LMNANPSR1KMT2AIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926168-A Polyether sulphone resin and preparation method thereof 吉林大学 2023-04-07 CN claimed
CN-110943253-A High-voltage lithium ion battery combined electrolyte additive, electrolyte and battery thereof 松山湖材料实验室 2020-03-31 CN claimed
EP-1027330-A4 STYRYL SULFONE ANTICANCER AGENTS UNIV TEMPLE (US) 2003-09-10 EP claimed
CN-1273580-A Styryl sulfone anticancer agents UNIV TEMPLE (US) 2000-11-15 CN claimed
EP-1027330-A1 STYRYL SULFONE ANTICANCER AGENTS Temple University of the Commonwealth System of Higher Education (US) 2000-08-16 EP claimed
WO-1999018068-A1 STYRYL SULFONE ANTICANCER AGENTS TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1999-04-15 WO claimed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-11745148-B2 Functionalized poly(diallylpiperidinium) and its copolymers for use in ion conducting applications COLORADO SCHOOL OF MINES (US) 2023-09-05 US disclosed
US-11427593-B2 Bromodomain inhibitor compound and use thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2022-08-30 US disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
US-20210178340-A1 FUNCTIONALIZED POLY(DIALLYLPIPERIDINIUM) AND ITS COPOLYMERS FOR USE IN ION CONDUCTING APPLICATIONS COLORADO SCHOOL OF MINES 2021-06-17 US disclosed
EP-3741758-A1 BROMODOMAIN INHIBITOR COMPOUND AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2020-11-25 EP disclosed
WO-1991015119-A1 SUBSTITUTED CYCLOHEXANEDIONES AND THEIR HERBICIDAL USES DOWELANCO (US) 1991-10-17 WO disclosed
EP-0450711-A1 Substituted cyclohexanediones and their herbicidal uses DOWELANCO (US) 1991-10-09 EP disclosed
US-5008369-A Preparation of polysulfones EASTMAN KODAK COMPANY (US) 1991-04-16 US disclosed
US-5006159-A Oximes, effective against grassy weeds but selective to broadleaf crops such as cotton, sugar beets, soybeans, wheat, rice and corn DOWELANCO (US) 1991-04-09 US disclosed
US-4931530-A Novel aromatic polyether and a process for producing an ether ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1990-06-05 US disclosed
EP-0268112-A2 A novel aromatic polyether and a process for producing a polyether Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-05-25 EP disclosed
US-4554381-A BORON TRIFLUORIDE, HYDROFLUORIC ACID RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1985-11-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11427593-B2 Bromodomain inhibitor compound and use thereof BRD4, BRD1, BRD3 USP2 2755/4885LMNA 2795/4885NPSR1 4138/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.