SCHEMBL422023

SCHEMBL422023

O=C1Cc2ccccc2C(=O)N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TDP2 O95551 16/20 1.00
▸ CASP3 P42574 1/20 1.00
▸ CASP7 P55210 1/20 1.00
▸ CASP9 P55211 1/20 1.00
▸ CASP6 P55212 1/20 1.00
▸ CASP8 Q14790 1/20 1.00
▸ MAP3K14 Q99558 1/20 1.00
▸ AHR P35869 1/20 0.57
▸ PDK2 Q15119 1/20 0.57
▸ GSK3B P49841 1/20 0.52
▸ MAOA P21397 1/20 0.52
▸ CA12 O43570 1/20 0.52
▸ CA9 Q16790 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580380 1.00 TDP2 (1.00) TDP2CASP3CASP7CASP9CASP6
Hydrochloric Acid SCHEMBL7001639 0.98 TDP2 (0.96) TDP2CASP3CASP7CASP9CASP6
Hydrochloric Acid SCHEMBL9377496 0.96 TDP2 (0.92) TDP2CASP3CASP7CASP9CASP6
Acetic Acid SCHEMBL9394441 0.89 TDP2 (0.79) TDP2CASP3CASP7CASP9CASP6
SCHEMBL31212786 0.89 TDP2 (0.79) TDP2CASP3CASP7CASP9CASP6
Pyrimidine SCHEMBL28527665 0.88 TDP2 (0.77) TDP2CASP3CASP7CASP9CASP6
SCHEMBL8563055 0.88 TDP2 (0.77) TDP2CASP3CASP7CASP9CASP6
Trifluoroacetic Acid SCHEMBL7370043 0.85 TDP2 (0.72) TDP2CASP3CASP7CASP9CASP6
Dimethylformamide SCHEMBL8783979 0.85 TDP2 (0.72) TDP2CASP3CASP7CASP9CASP6
Trifluoroacetic Acid SCHEMBL30633927 0.85 TDP2 (0.72) TDP2CASP3CASP7CASP9CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 648 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714928-A1 A REACTIVE RESIN COMPOSITION COMPRISING A PEROXIDE-FREE INITIATOR SYSTEM WITH A HETEROCYCLIC COMPOUND COMPRISING AT LEAST ONE N-N SINGLE BOND Hilti Aktiengesellschaft (LI) 2026-03-25 — — EP claimed
EP-4714926-A1 A REACTIVE RESIN COMPOSITION COMPRISING A PEROXIDE-FREE INITIATOR SYSTEM WITH A TERTIARY AMINE Hilti Aktiengesellschaft (LI) 2026-03-25 — — EP claimed
EP-4714927-A1 A REACTIVE RESIN COMPOSITION COMPRISING A PEROXIDE-FREE INITIATOR SYSTEM WITH A SULFINATE AND A TERTIARY AMINE Hilti Aktiengesellschaft (LI) 2026-03-25 — — EP claimed
EP-4714925-A1 A REACTIVE RESIN COMPOSITION COMPRISING A PEROXIDE-FREE INITIATOR SYSTEM Hilti Aktiengesellschaft (LI) 2026-03-25 — — EP claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 — — WO claimed
CN-119499245-A Peniazaphilone A use as alpha-glucosidase inhibitors and method for the production thereof 宜宾学院 2025-02-25 — — CN claimed
CN-117865922-A Formylcarboxylate coumarin compounds, methods of preparation and use thereof, and photoinitiator compositions containing same 湖北固润科技股份有限公司 2024-04-12 — — CN claimed
CN-115286556-B Preparation method of ester compound containing indolone or isoquinoline-1, 3-dione structure 浙江理工大学 2023-10-03 — — CN claimed
CN-116745295-A BRM targeting compounds and related methods of use 普莱鲁德疗法有限公司 2023-09-12 — — CN claimed
CN-116574089-A Synthesis method of 3, 3-disubstituted indolone or 4, 4-disubstituted isoquinoline dione compound 河南师范大学 2023-08-11 — — CN claimed
EP-0268093-B1 5-Nitrobenzo[de]isoquinoline-1,3 diones, their preparation and use KNOLL AG (DE) 1992-05-13 — — EP claimed
WO-1992000760-A1 METHOD OF TREATING NEUROLOGICAL DYSFUNCTION USING NEUROTRANSMITTER ENHANCES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1992-01-23 — — WO claimed
EP-0457243-A1 Novel tricyclic compounds SYNTEX (U.S.A.) INC. (US) 1991-11-21 — — EP claimed
EP-0384670-A2 Method for processing light sensitive silver halide color photographic material KONICA CORPORATION (JP) 1990-08-29 — — EP claimed
US-4824835-A Isoquinolinedione derivatives, pharmaceutical compositions and methods of use BOEHRINGER MANNHEIM GMBH (DE) 1989-04-25 — — US claimed
EP-0311010-A2 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1989-04-12 — — EP claimed
EP-0243808-A2 Isoquinolinediones, process for their preparation, and medicaments containing these compounds Roche Diagnostics GmbH (DE) 1987-11-04 — — EP claimed
US-4322487-A Composite electrically photosensitive particles for electrophoretic migration imaging process EASTMAN KODAK COMPANY (US) 1982-03-30 — — US claimed
US-4256819-A MEROCYANINES EASTMAN KODAK COMPANY (US) 1981-03-17 — — US claimed
EP-0024169-A2 Electrically photosensitive particles for electrophoretic migration imaging processes, dispersions of these particles, and processes using such dispersions EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-02-25 — — EP claimed
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