Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 16/20 | 0.72 |
| ▸ | CASP3 | P42574 | 1/20 | 0.72 |
| ▸ | CASP7 | P55210 | 1/20 | 0.72 |
| ▸ | CASP9 | P55211 | 1/20 | 0.72 |
| ▸ | CASP6 | P55212 | 1/20 | 0.72 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.72 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580380 | 0.85 | TDP2 (1.00) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL422023 | 0.85 | TDP2 (1.00) | TDP2CASP3CASP7CASP9CASP6 | |
| Hydrochloric Acid SCHEMBL7001639 | 0.83 | TDP2 (0.96) | TDP2CASP3CASP7CASP9CASP6 | |
| Hydrochloric Acid SCHEMBL9377496 | 0.81 | TDP2 (0.92) | TDP2CASP3CASP7CASP9CASP6 | |
| Acetic Acid SCHEMBL9394441 | 0.79 | TDP2 (0.79) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL8563055 | 0.78 | TDP2 (0.77) | TDP2CASP3CASP7CASP9CASP6 | |
| Phthalimide SCHEMBL27259393 | 0.77 | GSK3B (0.65) | TDP2CASP3CASP7CASP9CASP6 | |
| Phthalimide SCHEMBL14798718 | 0.76 | GSK3B (0.62) | TDP2CASP3CASP7CASP9CASP6 | |
| Phthalimide SCHEMBL14798719 | 0.76 | GSK3B (0.62) | TDP2CASP3CASP7CASP9CASP6 | |
| SCHEMBL31212786 | 0.76 | TDP2 (0.79) | TDP2CASP3CASP7CASP9CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674625-B1 | AMINO-SUBSTITUTED PYRAZOLES HAVING CRF ANTAGONISTIC ACTIVITY | PFIZER (US) | 1997-12-10 | — | — | EP | disclosed |