Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 8/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4219109 | 0.78 | GRIN1 (0.33) | RAB9A | |
| SCHEMBL31292095 | 0.70 | NOTUM (0.50) | RIPK1HSP90AA1NOTUMNAMPTHSP90AB1 | |
| SCHEMBL20609569 | 0.64 | ALDH1A1 (0.42) | RIPK1HSP90AA1NOTUMNAMPTHSP90AB1 | |
| SCHEMBL20609581 | 0.64 | RIPK1 (0.41) | RIPK1HSP90AA1NOTUMNAMPTHSP90AB1 | |
| Benzoic Acid SCHEMBL1071213 | 0.64 | TSHR (0.48) | RAB9A | |
| SCHEMBL27314978 | 0.63 | GRIN1 (0.45) | — | |
| Trifluoroacetic Acid SCHEMBL31197675 | 0.63 | NOTUM (0.42) | DPP8DPP9DPP7DPP4RIPK1 | |
| SCHEMBL10472848 | 0.62 | GRIN1 (0.44) | — | |
| SCHEMBL12571109 | 0.62 | DPP8 (0.67) | DPP8DPP9DPP7DPP4HSP90AA1 | |
| SCHEMBL416117 | 0.61 | GRIN1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074093-A2 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2009-07-01 | — | — | EP | claimed |
| WO-2008023336-A2 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2008-02-28 | — | — | WO | claimed |