SCHEMBL422143

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7889919	0.91	EPHX2 (0.38)	CYP3A4HDAC3HDAC4HDAC1HDAC7
	SCHEMBL10157300	0.85	EPHX2 (0.48)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL423878	0.83	EPHX2 (0.50)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL422000	0.83	EPHX2 (0.48)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL10157304	0.83	EPHX2 (0.45)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL421317	0.83	MEN1 (0.46)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL425024	0.82	EGLN1 (0.53)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL426163	0.81	EPHX2 (0.46)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL426609	0.81	EPHX2 (0.51)	HDAC3HDAC4HDAC1HDAC7HDAC2
	SCHEMBL421892	0.80	PKM (0.52)	EPHX2LIPEMEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.