Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL9087672 | 0.94 | ALDH1A1 (0.36) | ALDH1A1 | |
| Ether SCHEMBL2837591 | 0.93 | ALDH1A1 (0.37) | ALDH1A1THRBLMNA | |
| Ether SCHEMBL96502 | 0.93 | — | — | |
| Ether SCHEMBL8089271 | 0.93 | ALDH1A1 (0.37) | ALDH1A1THRBLMNA | |
| Ether SCHEMBL3794585 | 0.93 | ALDH1A1 (0.37) | ALDH1A1THRBLMNA | |
| Ether SCHEMBL3701280 | 0.93 | ALDH1A1 (0.37) | ALDH1A1THRBLMNA | |
| Ether SCHEMBL4944310 | 0.90 | ALDH1A1 (0.45) | ALDH1A1TSHRTHRB | |
| Hexane SCHEMBL10432593 | 0.88 | TSHR (0.37) | ALDH1A1TSHRTHRBLMNA | |
| Ether SCHEMBL28705136 | 0.86 | — | — | |
| Ether SCHEMBL28734827 | 0.86 | ALDH1A1 (0.33) | ALDH1A1THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12036294-B2 | Spherical rHDLs for targeted imaging | SIGNABLOK, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| US-20210205485-A1 | Spherical rHDLs For Targeted Imaging | SIGNABLOK, INC. | 2021-07-08 | — | — | US | disclosed |
| US-10894098-B2 | Methods and compositions for targeted imaging | SIGNABLOK, INC. (US) | 2021-01-19 | — | — | US | disclosed |
| US-20200339565-A1 | PRODRUG SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2020-10-29 | — | — | US | disclosed |
| US-20200101178-A1 | Methods And Compositions For Targeted Imaging | SIGNABLOK, INC. | 2020-04-02 | — | — | US | disclosed |
| US-20190248785-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2019-08-15 | — | — | US | disclosed |
| US-10202379-B2 | Substituted polycyclic carbamoyl pyridone derivative prodrug | SHIONOGI & CO., LTD. (JP) | 2019-02-12 | — | — | US | disclosed |
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |
| EP-2444400-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE | SHIONOGI & CO (JP) | 2018-03-28 | — | — | EP | disclosed |
| US-4866035-A | Dipeptidyl saccharides as host resistance enhancers in AIDS-immuno-compromised hosts and methods of use | MERCK & CO., INC. (US) | 1989-09-12 | — | — | US | disclosed |
| EP-0266006-A2 | Novel hypotensive diuretic peptides | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1988-05-04 | — | — | EP | disclosed |
| US-4672106-A | ANTITUMOR AGENTS | Hamaoka, Toshiyuki (JP) | 1987-06-09 | — | — | US | disclosed |
| EP-0192611-A2 | Acylated hexose derivatives and method for their preparation | CIBA-GEIGY AG (CH) | 1986-08-27 | — | — | EP | disclosed |
| EP-0173960-A2 | Muramylpeptide active ester derivatives | Hamaoka, Toshiyuki (JP) | 1986-03-12 | — | — | EP | disclosed |
| EP-0163286-A2 | Acylated sugars, method for their preparation and their use | CIBA-GEIGY AG (CH) | 1985-12-04 | — | — | EP | disclosed |
| US-4461763-A | CARDIOTONIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-07-24 | — | — | US | disclosed |
| US-4315031-A | Thiosubstituted amino acids | SCIENCE UNION ET CIE (FR) | 1982-02-09 | — | — | US | disclosed |
| US-4304772-A | Ethanocarbazole derivatives and antidepressant compositions | AYERST, MCKENNA & HARRISON, INC. (CA) | 1981-12-08 | — | — | US | disclosed |
| US-4107299-A | Cardioactive 12-epi-digoxin and derivatives thereof | BOEHRINGER MANNHEIM GMBH (DE) | 1978-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | ALDH1A1 1564/4885TSHR 3454/4885THRB 3578/4885 |
| US-20190248785-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | ALDH1A1 1564/4885TSHR 3454/4885THRB 3578/4885 |
| US-20200339565-A1 | PRODRUG SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | PREP, UNG, DPP4 | ALDH1A1 1478/4885TSHR 3454/4885THRB 3501/4885 |
| US-10202379-B2 | Substituted polycyclic carbamoyl pyridone derivative prodrug | PREP, UNG, DPP4 | ALDH1A1 1564/4885TSHR 3454/4885THRB 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.