Ether

Ether

SCHEMBL3794585

CCOCC.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl.ClC(Cl)Cl

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.37
THRB P10828 1/20 0.35
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL2837591 1.00 ALDH1A1 (0.37) ALDH1A1THRBLMNA
Ether SCHEMBL8089271 1.00 ALDH1A1 (0.37) ALDH1A1THRBLMNA
Ether SCHEMBL3701280 1.00 ALDH1A1 (0.37) ALDH1A1THRBLMNA
Ether SCHEMBL96502 1.00
Ether SCHEMBL28734827 0.93 ALDH1A1 (0.33) ALDH1A1THRBLMNA
Ether SCHEMBL422163 0.93 ALDH1A1 (0.40) ALDH1A1THRBLMNA
Ether SCHEMBL9750502 0.92
Ether SCHEMBL4944310 0.89 ALDH1A1 (0.45) ALDH1A1THRB
Ether SCHEMBL861634 0.88
1,1,2,2-Tetrachloroethane SCHEMBL28191474 0.88 TDP1 (0.39) ALDH1A1THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7754879-B2 Porphyrin compound, albumin inclusion compound thereof and artificial oxygen carrier NIPRO CORPORATION (JP) 2010-07-13 US disclosed
US-7595394-B2 Porphyrin compound, albumin inclusion compound thereof and artificial oxygen carrier NIPRO CORPORATION (JP) 2009-09-29 US disclosed
US-20090182125-A1 Porphyrin compound, albumin inclusion compound thereof and artificial oxygen carrier NIPRO CORPORATION (JP) 2009-07-16 US disclosed
EP-1466915-B1 Porphyrin compound, albumin inclusion compound thereof and artificial oxygen carrier NIPRO CORP (JP) 2006-11-02 EP disclosed
US-20060003923-A1 Porphyrin compound, albumin inclusion compound thereof and artificial oxygen carrier NIPRO CORPORATION 2006-01-05 US disclosed
EP-1466915-A1 Porphyrin compound, albumin inclusion compound thereof and artificial oxygen carrier Nipro Corporation (JP) 2004-10-13 EP disclosed
US-20040180837-A1 Porphyrin compound, albumin inclusion compound thereof and artificial oxygen carrier NIPRO CORPORATION 2004-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040180837-A1 Porphyrin compound, albumin inclusion compound thereof and artificial oxygen carrier ALB, SLC40A1, FTH1 ALDH1A1 2031/4885THRB 4307/4885LMNA 4050/4885
US-20090182125-A1 Porphyrin compound, albumin inclusion compound thereof and artificial oxygen carrier ALB, SLC40A1, FTH1 ALDH1A1 2401/4885THRB 4241/4885LMNA 4033/4885
US-20060003923-A1 Porphyrin compound, albumin inclusion compound thereof and artificial oxygen carrier ALB, SLC40A1, FTH1 ALDH1A1 2401/4885THRB 4241/4885LMNA 4033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.