Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5676040 | 0.97 | TSHR (0.47) | TSHRGABRA1GABRB1CNR1CNR2 | |
| SCHEMBL11574451 | 0.94 | GABRA1 (0.46) | TSHRGABRA1GABRB1CNR1CNR2 | |
| Hydrogen Peroxide SCHEMBL11577393 | 0.88 | GABRA1 (0.48) | TSHRGABRA1GABRB1CNR1CNR2 | |
| SCHEMBL6124148 | 0.84 | GABRA1 (0.39) | TSHRGABRA1GABRB1CNR1CNR2 | |
| SCHEMBL16959948 | 0.82 | GABRA1 (0.38) | TSHRGABRA1GABRB1CNR1CNR2 | |
| SCHEMBL20844085 | 0.82 | GABRA1 (0.38) | TSHRGABRA1GABRB1CNR1CNR2 | |
| SCHEMBL9967735 | 0.82 | GABRA1 (0.38) | TSHRGABRA1GABRB1CNR1CNR2 | |
| SCHEMBL4547915 | 0.82 | TRPM8 (0.38) | TSHRGABRA1GABRB1CNR1CNR2 | |
| SCHEMBL13523275 | 0.82 | GABRA1 (0.48) | TSHRGABRA1GABRB1CNR1CNR2 | |
| SCHEMBL3791553 | 0.82 | CYP3A4 (0.55) | TSHRGABRA1GABRB1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 658 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529789-B | Synthetic process of 3,5-dichloro-alpha,alpha-dimethyl benzylamine | 苏州市玮琪生物科技有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-104529789-A | Synthetic process of 3,5-dichloro-alpha,alpha-dimethyl benzylamine | SUZHOU WELL BRIDGE BIOLOG TECHNOLOGY CO LTD | 2015-04-22 | — | — | CN | claimed |
| EP-0322869-B1 | PROCESS FOR SEPARATING DICHLOROCUMENE ISOMER | TORAY INDUSTRIES, INC. (JP) | 1992-09-09 | — | — | EP | claimed |
| US-5030777-A | Synthesis of 3,5-dichloroalkylbenzene and recovery of 1,3-dichlorobenzene | STANDARD CHLORINE OF DELAWARE, INC. (US) | 1991-07-09 | — | — | US | claimed |
| EP-0322869-A2 | Process for separating dichlorocumene isomer | TORAY INDUSTRIES, INC. (JP) | 1989-07-05 | — | — | EP | claimed |
| EP-0090875-B1 | SEPARATION OF 3,5-DICHLOROCUMENE FROM A MIXTURE OF 3,5-DICHLOROCUMENE AND 2,4-DICHLOROCUMENE | THE DOW CHEMICAL COMPANY (US) | 1985-07-31 | — | — | EP | claimed |
| EP-0061720-B1 | PROCESS FOR THE SELECTIVE ALIPHATIC CHLORINATION OF ALKYLBENZENES | THE DOW CHEMICAL COMPANY (US) | 1985-03-13 | — | — | EP | claimed |
| EP-0090875-A1 | Separation of 3,5-dichlorocumene from a mixture of 3,5-dichlorocumene and 2,4-dichlorocumene | THE DOW CHEMICAL COMPANY (US) | 1983-10-12 | — | — | EP | claimed |
| EP-0061720-A1 | Process for the selective aliphatic chlorination of alkylbenzenes | THE DOW CHEMICAL COMPANY (US) | 1982-10-06 | — | — | EP | claimed |
| US-4348265-A | Process for the selective aliphatic chlorination of alkylbenzenes | THE DOW CHEMICAL COMPANY (US) | 1982-09-07 | — | — | US | claimed |
| US-4329524-A | Separation of 3,5-dichlorocumene from a mixture of 3,5-dichlorocumene and 2,4-dichlorocumene | THE DOW CHEMICAL COMPANY (US) | 1982-05-11 | — | — | US | claimed |
| US-4104315-A | Process for separating an ar, ar-dihalo-ar-alkylbenzene from an isomeric mixture of ar, ar-dihalo-ar-alkylbenzenes | THE DOW CHEMICAL COMPANY (US) | 1978-08-01 | — | — | US | claimed |
| JP-2178240-A | — | — | None | — | — | JP | disclosed |
| JP-1319444-A | — | — | None | — | — | JP | disclosed |
| US-20240239772-A1 | PROTEASE INHIBITORS AND METHODS OF USE | THE CLEVELAND CLINIC FOUNDATION | 2024-07-18 | — | — | US | disclosed |
| US-20240239772-A1 | PROTEASE INHIBITORS AND METHODS OF USE | THE CLEVELAND CLINIC FOUNDATION | 2024-07-18 | — | — | US | disclosed |
| US-4104315-A | Process for separating an ar, ar-dihalo-ar-alkylbenzene from an isomeric mixture of ar, ar-dihalo-ar-alkylbenzenes | THE DOW CHEMICAL COMPANY (US) | 1978-08-01 | — | — | US | disclosed |
| US-4087473-A | Preferential aliphatic halogenation of ar-substituted alkylbenzenes | THE DOW CHEMICAL COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4087473-A | Preferential aliphatic halogenation of ar-substituted alkylbenzenes | THE DOW CHEMICAL COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4059642-A | Preferential alkylation or acylation of meta-disubstituted benzenes | THE DOW CHEMICAL COMPANY (US) | 1977-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240239772-A1 | PROTEASE INHIBITORS AND METHODS OF USE | ACE2, ACE, TMPRSS2 | TSHR 4756/4885GABRA1 3840/4885GABRB1 3878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.