Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7590925 | 0.78 | TAAR1 (0.54) | TAAR1MITFIDO1CYP1A2CYP2D6 | |
| SCHEMBL27997934 | 0.78 | TAAR1 (0.71) | TAAR1IDO1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL237082 | 0.74 | TAAR1 (0.54) | TAAR1MITFPYCR1ALDH1A1 | |
| SCHEMBL9018624 | 0.74 | MITF (0.47) | TAAR1MITFCYP3A4PYCR1ALDH1A1 | |
| SCHEMBL9642112 | 0.72 | TAAR1 (0.62) | TAAR1IDO1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL29661804 | 0.72 | TAAR1 (0.62) | TAAR1IDO1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11010381 | 0.72 | TAAR1 (0.62) | TAAR1IDO1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28097582 | 0.71 | CYP1A2 (0.48) | MITFCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL27627209 | 0.71 | DPP4 (0.50) | MITFHTR7ALDH1A1HSD17B10 | |
| SCHEMBL3055393 | 0.70 | TAAR1 (1.00) | TAAR1IDO1CYP1A2CYP2D6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105278-A1 | Selective inhibitors of human corticosteroid syntheses | UNIVERSITAT DES SAARLANDES (DE) | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105278-A1 | Selective inhibitors of human corticosteroid syntheses | HSD11B1, HSD11B2, CYP11B1 | TAAR1 3434/4885MITF 1942/4885IDO1 1806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.