SCHEMBL42227

SCHEMBL42227

Oc1ncc(Cl)c(O)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29835263 1.00
SCHEMBL15769475 0.79
SCHEMBL2490205 0.75
SCHEMBL27820381 0.75
SCHEMBL12878591 0.75
SCHEMBL149516 0.72
SCHEMBL20267532 0.72 KDM4E (0.43)
Water SCHEMBL29599612 0.70
SCHEMBL23937701 0.70 FTO (0.39)
SCHEMBL11432532 0.70 GLP1R (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114829344-A Novel pyrimidine derivative and use thereof 韩国化学研究院 2022-07-29 CN claimed
CN-110452355-B Self-repairing rat-proof and termite-proof polyurethane, preparation method and application 安徽建筑大学 2021-07-16 CN claimed
EP-3486234-B1 ARYL- OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS EPIZYME INC (US) 2021-06-02 EP claimed
CN-1615314-A Phospholipid derivatives of nucleosides as antitumor agents HEIDELBERG PHARMA HOLDING GMBH (DE) 2005-05-11 CN claimed
US-20050090659-A1 Phospholepid derivatives of nucleosides as antitumaorl medicaments GANYMED 256 VERMOEGENSVERWALTUNGS GMBH (DE) 2005-04-28 US claimed
EP-1448579-A1 PHOSPHOLIPID DERIVATIVES OF NUCLEOSIDES AS ANTITUMORAL MEDICAMENTS Heidelberg Pharma Holding GmbH (DE) 2004-08-25 EP claimed
WO-2003044035-A1 PHOSPHOLIPID DERIVATIVES OF NUCLEOSIDES AS ANTITUMORAL MEDICAMENTS GANYMED 256 VERMÖGENSVERWALTUNGS GMBH (DE) 2003-05-30 WO claimed
US-20260124314-A1 ANTl-5T4 ANTIGEN BINDING DOMAINS, ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF SALUBRIS BIOTHERAPEUTICS INC (US) 2026-05-07 US disclosed
US-12600704-B2 Substituted 1,2,4-triazoles and methods of use STINGINN LLC (US) 2026-04-14 US disclosed
US-20260069620-A1 IMMUNOTHERAPEUTIC PHOSPHOLIPIDS FOR CANCER TREATMENT UNIVERSITY OF CINCINNATI (US) 2026-03-12 US disclosed
US-20260014253-A1 CHECKPOINT REGULATOR ANTAGONISTS GENSUN BIOPHARMA INC (US) 2026-01-15 US disclosed
WO-2025245112-A1 NEUREGULIN-1/ANTI-HER3 ANTIBODY FUSION PROTEIN FOR USE IN THE TREATMENT OF HEART FAILURE SALUBRIS BIOTHERAPEUTICS, INC. (US) 2025-11-27 WO disclosed
US-20250361306-A1 ANTITUMOR IMMUNE CHECKPOINT REGULATOR ANTAGONISTS GENSUN BIOPHARMA INC (US) 2025-11-27 US disclosed
CN-100360564-C Peptides and peptidomimetics having antiproliferative activity and/or enhancing the effect of nucleic acid damaging agents or treatments CANBAS RES LAB LTD (JP) 2008-01-09 CN disclosed
CN-101092455-A Peptides and peptidomimetics having anti-proliferative activity and/or that augment nucleic acid damaging agents or treatments CANBAS CO LTD (JP) 2007-12-26 CN disclosed
CN-1642978-A Peptides and peptidomimetics having antiproliferative activity and/or enhancing the effect of nucleic acid damaging agents or treatments CANBAS RES LAB LTD (JP) 2005-07-20 CN disclosed
CN-1615314-A Phospholipid derivatives of nucleosides as antitumor agents HEIDELBERG PHARMA HOLDING GMBH (DE) 2005-05-11 CN disclosed
US-20050090659-A1 Phospholepid derivatives of nucleosides as antitumaorl medicaments GANYMED 256 VERMOEGENSVERWALTUNGS GMBH (DE) 2005-04-28 US disclosed
EP-1448579-A1 PHOSPHOLIPID DERIVATIVES OF NUCLEOSIDES AS ANTITUMORAL MEDICAMENTS Heidelberg Pharma Holding GmbH (DE) 2004-08-25 EP disclosed
WO-2003044035-A1 PHOSPHOLIPID DERIVATIVES OF NUCLEOSIDES AS ANTITUMORAL MEDICAMENTS GANYMED 256 VERMÖGENSVERWALTUNGS GMBH (DE) 2003-05-30 WO disclosed