SCHEMBL4223

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4655	0.94	SLC18A3 (0.45)	CYP1A2MEN1KMT2ASMN1; SMN2SLC18A3
	SCHEMBL3552	0.94	DRD2 (0.44)	CYP1A2MAPTCYP2C9CYP2C19MEN1
	Bicarbonate SCHEMBL18167182	0.86	ACKR3 (0.44)	CYP1A2KMT2ASMN1; SMN2SLC18A3DRD2
	Bicarbonate SCHEMBL18167217	0.82	OGA (0.45)	CYP1A2MEN1KMT2ANPC1RAB9A
	SCHEMBL4086	0.81	ABCC3 (0.46)	CYP2C9ACKR3HCRTR1HCRTR2
	Bicarbonate SCHEMBL18167233	0.81	DRD2 (0.42)	MEN1KMT2ANPC1RAB9ADRD2
	SCHEMBL4483	0.78	OPRM1 (0.45)	—
	SCHEMBL11226	0.77	DRD2 (0.37)	MEN1KMT2ADRD2CYP2D6DRD4
	SCHEMBL3630	0.76	ABCC3 (0.47)	CYP2C9SMN1; SMN2HTT
	SCHEMBL15084374	0.75	HRH3 (0.45)	MAPTCYP2C19MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.